about
Promoter hypermethylation of the SFRP2 gene is a high-frequent alteration and tumor-specific epigenetic marker in human breast cancerTranscriptional downregulation of gap-junction proteins blocks junctional communication in human mammary tumor cell linesDown-regulation of a member of the S100 gene family in mammary carcinoma cells and reexpression by azadeoxycytidine treatmentLoss of both CSF1R (FMS) alleles in patients with myelodysplasia and a chromosome 5 deletionChromosome 7 suppresses indefinite division of nontumorigenic immortalized human fibroblast cell lines KMST-6 and SUSM-1An overexpressed gene transcript in senescent and quiescent human fibroblasts encoding a novel protein in the epidermal growth factor-like repeat family stimulates DNA synthesisIdentification and partial characterization of a novel membrane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growthGene therapy in clinical medicineThrombospondin type 1 repeats interact with matrix metalloproteinase 2. Regulation of metalloproteinase activityIdentification of drm, a novel gene whose expression is suppressed in transformed cells and which can inhibit growth of normal but not transformed cells in cultureLoss of constitutional heterozygosity on chromosome 5q in hepatocellular carcinoma without cirrhosis.Molecular mechanisms of cancer.Epidemiologic evidence for the increased cell proliferation model of carcinogenesisAssociation between TP53 gene Arg72Pro polymorphism and Wilms' tumor risk in a Chinese population.Molecular cloning of lin-29, a heterochronic gene required for the differentiation of hypodermal cells and the cessation of molting in C.elegans.Positive selection of candidate tumor-suppressor genes by subtractive hybridization.The TP53 gene rs1042522 C>G polymorphism and neuroblastoma risk in Chinese children.Dietary antioxidants, cancer, and atherosclerotic heart disease.Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53.A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondinLoss of heterozygosity on chromosomes 17 and 18 in breast carcinoma: two additional regions identified.Growth-related gene expression in type 2 alveolar epithelial cells.Towards a molecular approach to gastric cancer management.Cytokine therapeutics: lessons from interferon alphaSenescence as a mode of tumor suppressionMolecular and functional analysis of tumor-suppressor genes by transfectionFrequency and spectrum of mutations at codons 12 and 13 of the c-K-ras gene in human tumors.Loss of heterozygosity for alleles on chromosome II in cervical carcinoma.Hepatitis B virus infection and primary hepatocellular carcinoma.The cultured diploid fibroblast as a model for the study of cellular aging.Human replicative senescence. A molecular studyOverexpression of p53 protein in basal cell carcinomas of human skinExtinction of the HPV18 upstream regulatory region in cervical carcinoma cells after fusion with non-tumorigenic human keratinocytes under non-selective conditionsProtein kinase C activation potently down-regulates the expression of its major substrate, 80K, in Swiss 3T3 cells.Cervical carcinoma: low frequency of allele loss at loci implicated in other common malignancies.Interactions of miR-34b/c and TP53 polymorphisms on the risk of intracranial aneurysm.Expression of the major protein kinase C substrate, the acidic 80-kilodalton myristoylated alanine-rich C kinase substrate, increases sharply when Swiss 3T3 cells move out of cycle and enter G0Isolation and characterization of a novel mitogenic regulatory gene, 322, which is transcriptionally suppressed in cells transformed by src and rasLoss of p53 protein during radiation transformation of primary human mammary epithelial cells.Alterations of the p53 gene in nasopharyngeal carcinoma.
P2860
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P2860
description
1989 nî lūn-bûn
@nan
1989 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Tumor suppressor genes: the puzzle and the promise.
@ast
Tumor suppressor genes: the puzzle and the promise.
@en
type
label
Tumor suppressor genes: the puzzle and the promise.
@ast
Tumor suppressor genes: the puzzle and the promise.
@en
prefLabel
Tumor suppressor genes: the puzzle and the promise.
@ast
Tumor suppressor genes: the puzzle and the promise.
@en
P356
P1433
P1476
Tumor suppressor genes: the puzzle and the promise.
@en
P2093
P304
P356
10.1126/SCIENCE.2574499
P407
P577
1989-12-01T00:00:00Z