A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties.

A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties.

Item
http://www.wikidata.org/entity/Q33363170
Metalloproteinase inhibitors, nonantimicrobial chemically modified tetracyclines, and ilomastat block Bacillus anthracis lethal factor activity in viable cellsCytotoxic effects of tetracycline analogues (doxycycline, minocycline and COL-3) in acute myeloid leukemia HL-60 cellsPhase I and pharmacokinetic study of COL-3 in patients with recurrent high-grade gliomasThe clinical relevance of stromal matrix metalloproteinase expression in ovarian cancer.Phase I study of continuous weekly dosing of dimethylamino benzoylphenylurea (BPU) in patients with solid tumours.Emerging drugs for the treatment of soft tissue sarcomas.Evaluation of the Safety and Benefit of Phase I Oncology Trials for Patients With Primary CNS Tumors.Biotic acts of antibioticsStromal Modulators of TGF-β in Cancer.Pharmacodynamic considerations in the use of matrix metalloproteinase inhibitors in cancer treatment.Radiotherapy-induced gut toxicity: Involvement of matrix metalloproteinases and the intestinal microvasculature.Intricate Functions of Matrix Metalloproteinases in Physiological and Pathological Conditions.Fisetin inhibits matrix metalloproteinases and reduces tumor cell invasiveness and endothelial cell tube formation.Tetracycline analogues (doxycycline and COL-3) induce caspase-dependent and -independent apoptosis in human colon cancer cells.Structural and dynamics analysis of matrix metalloproteinases MMP-2 complexed with chemically modified tetracyclines (CMTs).Phase II prospective study with sorafenib in advanced soft tissue sarcomas after anthracycline-based therapy.Mitochondria as oncotarget: a comparison between the tetracycline analogs doxycycline and COL-3
P2860

A phase I and pharmacokinetic study of Col-3 (Metastat), an oral tetracycline derivative with potent matrix metalloproteinase and antitumor properties.

Item
http://www.wikidata.org/entity/Q33363170
description
2004 nî lūn-bûn
@nan
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
A phase I and pharmacokinetic ...... nase and antitumor properties.
@ast
A phase I and pharmacokinetic ...... nase and antitumor properties.
@en
type
label
A phase I and pharmacokinetic ...... nase and antitumor properties.
@ast
A phase I and pharmacokinetic ...... nase and antitumor properties.
@en
prefLabel
A phase I and pharmacokinetic ...... nase and antitumor properties.
@ast
A phase I and pharmacokinetic ...... nase and antitumor properties.
@en
P1433
P1476
P2093
P304
P31
P356
P407
P433
P478
P50
P577
P698
P356
P1433
P1476
A phase I and pharmacokinetic ...... nase and antitumor properties.
@en
P2093
P304
P31
P356
10.1158/1078-0432.CCR-04-0804
P407
P433
P478
P50
P577
P698