A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis. - Wikidata - wikimedia - TriplyDB

A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis.

A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis.

http://www.wikidata.org/entity/Q33367112

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Strategies for treatment in Alexander disease Mechanisms of glutamate transport Current approaches to enhance glutamate transporter function and expression High-affinity glutamate transporters in chronic pain: an emerging therapeutic target Design and initial results of a multi-phase randomized trial of ceftriaxone in amyotrophic lateral sclerosis Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis.Decreased expression of GLT-1 in the R6/2 model of Huntington's disease does not worsen disease progression.Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection Identification of translational activators of glial glutamate transporter EAAT2 through cell-based high-throughput screening: an approach to prevent excitotoxicity.Multiple changes in peptide and lipid expression associated with regeneration in the nervous system of the medicinal leech.Clavulanic acid reduces rewarding, hyperthermic and locomotor-sensitizing effects of morphine in rats: a new indication for an old drug?Spinal upregulation of glutamate transporter GLT-1 by ceftriaxone: therapeutic efficacy in a range of experimental nervous system disorders.Regulation of xCT expression and system x (c) (-) function in neuronal cells.Safety and efficacy of ceftriaxone for amyotrophic lateral sclerosis: a multi-stage, randomised, double-blind, placebo-controlled trial.TRPM2 cation channels modulate T cell effector functions and contribute to autoimmune CNS inflammation.Comparison of Effect of One Course of Intense Exercise (Wingate test) on Serum Levels of Interleukin-17 in Different Groups of Athletes.Antibiotic treatment attenuates behavioral and neurochemical changes induced by exposure of rats to group a streptococcal antigen Preclinical Rodent Toxicity Studies for Long Term Use of Ceftriaxone Neuropathic pain in animal models of nervous system autoimmune diseases.Biotic acts of antibiotics Purkinje cell loss in experimental autoimmune encephalomyelitis.Clinical veterinarian's perspective of non-human primate (NHP) use in drug safety studies.Effects of opioids, cannabinoids, and vanilloids on body temperature.The role of glutamate and its receptors in multiple sclerosis.Experimental trials in amyotrophic lateral sclerosis: a review of recently completed, ongoing and planned trials using existing and novel drugs.Glutamate transporter EAAT2: regulation, function, and potential as a therapeutic target for neurological and psychiatric disease.Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats Brain endothelial cells induce astrocytic expression of the glutamate transporter GLT-1 by a Notch-dependent mechanism.Astroglial glutamate transporters in the brain: Regulating neurotransmitter homeostasis and synaptic transmission.An astroglial basis of major depressive disorder? An overview.Gut-CNS-Axis as Possibility to Modulate Inflammatory Disease Activity-Implications for Multiple Sclerosis Regulation of glial glutamate transporters by C-terminal domains.Cocaine-induced loss of white matter proteins in the adult mouse nucleus accumbens is attenuated by administration of a β-lactam antibiotic during cocaine withdrawal.Excitotoxic neuronal cell death during an oligodendrocyte-directed CD8+ T cell attack in the CNS gray matter.The β-lactam clavulanic acid mediates glutamate transport-sensitive pain relief in a rat model of neuropathic pain.Gut Microbiota Confers Resistance of Albino Oxford Rats to the Induction of Experimental Autoimmune Encephalomyelitis.

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P2860

A beta-lactam antibiotic dampens excitotoxic inflammatory CNS damage in a mouse model of multiple sclerosis.

http://www.wikidata.org/entity/Q33367112

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Alla L Zozulya

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Christian Weidenfeller

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Martin Stangel

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Nico Melzer

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P2860

Functional comparisons of three glutamate transporter subtypes cloned from human motor cortex

Mechanism of ceftriaxone induction of excitatory amino acid transporter-2 expression and glutamate uptake in primary human astrocytes

Glutamate uptake

Flux coupling in a neuronal glutamate transporter

Expression of a variant form of the glutamate transporter GLT1 in neuronal cultures and in neurons and astrocytes in the rat brain

Epilepsy and exacerbation of brain injury in mice lacking the glutamate transporter GLT-1

Preparation of separate astroglial and oligodendroglial cell cultures from rat cerebral tissue

An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow

Benzylpenicillin differentially conjugates to IFN-gamma, TNF-alpha, IL-1beta, IL-4 and IL-13 but selectively reduces IFN-gamma activity.

Axonal and neuronal degeneration in multiple sclerosis: mechanisms and functional consequences.

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multiple sclerosis

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