Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation - Wikidata - wikimedia - TriplyDB

Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation

Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation

http://www.wikidata.org/entity/Q33367565

about

Regulatory T Cells: Serious Contenders in the Promise for Immunological Tolerance in Transplantation Regulatory T-cell therapy in transplantation: moving to the clinic Novel GMP-compatible protocol employing an allogeneic B cell bank for clonal expansion of allospecific natural regulatory T cells.Perspectives on Regulatory T Cell Therapies.The soluble isoform of CTLA-4 as a regulator of T-cell responses.Transplantation tolerance: Clinical potential of regulatory T cells.Stability of human rapamycin-expanded CD4+CD25+ T regulatory cells Generation, cryopreservation, function and in vivo persistence of ex vivo expanded cynomolgus monkey regulatory T cells.Harnessing regulatory T cells for the treatment of inflammatory bowel disease.Lysosomal-associated Transmembrane Protein 4B (LAPTM4B) Decreases Transforming Growth Factor β1 (TGF-β1) Production in Human Regulatory T Cells.Freeze and Thaw of CD4+CD25+Foxp3+ Regulatory T Cells Results in Loss of CD62L Expression and a Reduced Capacity to Protect against Graft-versus-Host Disease.Oligodeoxynucleotides stabilize Helios-expressing Foxp3+ human T regulatory cells during in vitro expansion.A TNFR2-Agonist Facilitates High Purity Expansion of Human Low Purity Treg Cells.TGF-β in tolerance, development and regulation of immunity Selective expression of latency-associated peptide (LAP) and IL-1 receptor type I/II (CD121a/CD121b) on activated human FOXP3+ regulatory T cells allows for their purification from expansion cultures Isolation of functional human regulatory T cells (Treg) from the peripheral blood based on the CD39 expression.Rhesus monkey immature monocyte-derived dendritic cells generate alloantigen-specific regulatory T cells from circulating CD4+CD127-/lo T cells.Regulatory T cells as therapeutic targets in rheumatoid arthritis.Immunotherapy with regulatory T cells in transplantation.What are regulatory T cells (Treg) regulating in cancer and why?Induced and natural regulatory T cells in human cancer.Promoting transplantation tolerance; adoptive regulatory T cell therapy.Regulatory T cells as immunotherapy.Improving engraftment and immune reconstitution in umbilical cord blood transplantation.Therapeutic potential of umbilical cord blood cells for type 1 diabetes mellitus.Regulatory T cells: first steps of clinical application in solid organ transplantation.Clinical grade isolation of regulatory T cells from G-CSF mobilized peripheral blood improves with initial depletion of monocytes.Tregs: hype or hope for allogeneic hematopoietic stem cell transplantation?Treg therapy in transplantation: a general overview.Optimization of cGMP purification and expansion of umbilical cord blood-derived T-regulatory cells in support of first-in-human clinical trials.Restimulation After Cryopreservation and Thawing Preserves the Phenotype and Function of Expanded Baboon Regulatory T Cells.Generation of donor-specific Tr1 cells to be used after kidney transplantation and definition of the timing of their in vivo infusion in the presence of immunosuppression.Cell Therapy in Kidney Transplantation: Focus on Regulatory T Cells.Expanding Diversity and Common Goal of Regulatory T and B Cells. II: In Allergy, Malignancy, and Transplantation.T-cell subsets in autologous and allogeneic peripheral blood stem cell concentrates.Multiple unit pooled umbilical cord blood is a viable source of therapeutic regulatory T cells.Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets Efficient expansion of cryopreserved CD4(+)CD25(+)CD127(lo/-) cells in Type 1 diabetes.Adenosine and prostaglandin e2 production by human inducible regulatory T cells in health and disease.Good Manufacturing Practice-Compliant Production and Lot-Release of Ex Vivo Expanded Regulatory T Cells As Basis for Treatment of Patients with Autoimmune and Inflammatory Disorders.

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Clinical grade Treg: GMP isolation, improvement of purity by CD127 Depletion, Treg expansion, and Treg cryopreservation

http://www.wikidata.org/entity/Q33367565

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

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Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

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Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

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Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

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Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

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Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

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JOURNAL.PONE.0003161

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Clinical grade Treg: GMP isola ...... ion, and Treg cryopreservation

@en

P2093

Frank W Preijers

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Hans J P M Koenen

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Irma Joosten

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Jorieke H Peters

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Rob Woestenenk

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P2860

CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells

Ex vivo generation of human alloantigen-specific regulatory T cells from CD4(pos)CD25(high) T cells for immunotherapy

B cell lymphoproliferative disorders following hematopoietic stem cell transplantation: risk factors, treatment and outcome.

Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemia

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells.

Effective expansion of alloantigen-specific Foxp3+ CD25+ CD4+ regulatory T cells by dendritic cells during the mixed leukocyte reaction.

Post-transplant lymphoproliferative disorders (PTLD) after solid organ transplantation.

Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T cells.

Donor-type CD4(+)CD25(+) regulatory T cells suppress lethal acute graft-versus-host disease after allogeneic bone marrow transplantation.

In vitro-expanded antigen-specific regulatory T cells suppress autoimmune diabetes.

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e3161

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10.1371/JOURNAL.PONE.0003161

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9

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3

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Luuk B Hilbrands

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2008-09-08T00:00:00Z

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P5875

23242865

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18776930

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cryopreservation

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2522271

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