Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells - Wikidata - wikimedia - TriplyDB

Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells

Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells

http://www.wikidata.org/entity/Q33372124

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Receptor complexes for each of the Class 3 Semaphorins An image-based RNAi screen identifies SH3BP1 as a key effector of Semaphorin 3E-PlexinD1 signaling The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subunits of the human Ccr4-Not complex contribute to the prevention of cell death and senescence Lymphangiogenesis and metastasis--a closer look at the neuropilin/semaphorin3 axis Neuropilins: expression and roles in the epithelium Semaphorin 3A suppresses tumor growth and metastasis in mice melanoma model CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies Semaphorin 3d signaling defects are associated with anomalous pulmonary venous connections Semaphorin 3A Increases FAK Phosphorylation at Focal Adhesions to Modulate MDA-MB-231 Cell Migration and Spreading on Different Substratum Concentrations Semaphorin-3D and semaphorin-3E inhibit the development of tumors from glioblastoma cells implanted in the cortex of the brain.Plexin D1 is ubiquitously expressed on tumor vessels and tumor cells in solid malignancies.The cleavage of semaphorin 3C induced by ADAMTS1 promotes cell migration Hormonal regulation and distinct functions of semaphorin-3B and semaphorin-3F in ovarian cancer.Genome wide screen identifies microsatellite markers associated with acute adverse effects following radiotherapy in cancer patients Sema3E-Plexin D1 signaling drives human cancer cell invasiveness and metastatic spreading in mice Semaphorin 3d and semaphorin 3e direct endothelial motility through distinct molecular signaling pathways.RORα suppresses breast tumor invasion by inducing SEMA3F expression Diverse functions for the semaphorin receptor PlexinD1 in development and disease.Decreased semaphorin3A expression correlates with disease activity and histological features of rheumatoid arthritis.Reverse differentiation as a gene filtering tool in genome expression profiling of adipogenesis for fat marker gene selection and their analysis.Semaphorins in angiogenesis and tumor progression.Integration of repulsive guidance cues generates avascular zones that shape mammalian blood vessels.Regulation of mTOR Signaling by Semaphorin 3F-Neuropilin 2 Interactions In Vitro and In Vivo.Semaphorin signaling in angiogenesis, lymphangiogenesis and cancer Tumour growth inhibition and anti-metastatic activity of a mutated furin-resistant Semaphorin 3E isoform.Increased smooth muscle contractility in mice deficient for neuropilin 2.The Expansion of CD25 high IL-10 high FoxP3 high B Regulatory Cells Is in Association with SLE Disease Activity.Semaphorin 3A is a marker for disease activity and a potential immunoregulator in systemic lupus erythematosus.Epigenetically downregulated Semaphorin 3E contributes to gastric cancer Expression of VEGF and semaphorin genes define subgroups of triple negative breast cancer Axon guidance molecule semaphorin3A is a novel tumor suppressor in head and neck squamous cell carcinoma The evaluative value of Sema3C and MFN2 co-expression detected by immunohistochemistry for prognosis in hepatocellular carcinoma patients after hepatectomy.Semaphorin 3A is an endogenous angiogenesis inhibitor that blocks tumor growth and normalizes tumor vasculature in transgenic mouse models.Expression of semaphorin 6D and its receptor plexin-A1 in gastric cancer and their association with tumor angiogenesis.Decreased expression of semaphorin 3D is associated with genesis and development in colorectal cancer.Signal transduction in vasculogenesis and developmental angiogenesis Class 3 semaphorins and their receptors in physiological and pathological angiogenesis.Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis.Class 3 semaphorins as a therapeutic target.Neuropilins: a new target for cancer therapy.

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Successful inhibition of tumor development by specific class-3 semaphorins is associated with expression of appropriate semaphorin receptors by tumor cells

http://www.wikidata.org/entity/Q33372124

description

2008 nî lūn-bûn

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2008 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի սեպտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

Successful inhibition of tumor ...... horin receptors by tumor cells

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Successful inhibition of tumor ...... horin receptors by tumor cells

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type

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Successful inhibition of tumor ...... horin receptors by tumor cells

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Successful inhibition of tumor ...... horin receptors by tumor cells

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Successful inhibition of tumor ...... horin receptors by tumor cells

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Successful inhibition of tumor ...... horin receptors by tumor cells

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Successful inhibition of tumor ...... horin receptors by tumor cells

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Asya Varshavsky

http://www.w3.org/2001/XMLSchema#string

Boaz Kigel

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Gera Neufeld

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Ofra Kessler

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P2860

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates

Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

Neuropilin is a semaphorin III receptor

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

Semaphorin SEMA3F and VEGF have opposing effects on cell attachment and spreading

Inhibition of lung cancer cell growth and induction of apoptosis after reexpression of 3p21.3 candidate tumor suppressor gene SEMA3B

Semaphorin 3F, a chemorepulsant for endothelial cells, induces a poorly vascularized, encapsulated, nonmetastatic tumor phenotype.

Neuropilin-2, a novel member of the neuropilin family, is a high affinity receptor for the semaphorins Sema E and Sema IV but not Sema III

Neuropilin-2 is a receptor for the vascular endothelial growth factor (VEGF) forms VEGF-145 and VEGF-165 [corrected]

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors

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