Scaffold diversity of natural products: inspiration for combinatorial library design.
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Cancer wars: natural products strike backNatural-product-derived fragments for fragment-based ligand discoveryInCHlib – interactive cluster heatmap for web applicationsUse of natural products as chemical library for drug discovery and network pharmacologyAfroDb: a select highly potent and diverse natural product library from African medicinal plantsNew antimalarial hits from Dacryodes edulis (Burseraceae)--part I: isolation, in vitro activity, in silico "drug-likeness" and pharmacokinetic profilesModern natural products drug discovery and its relevance to biodiversity conservationIn silico drug metabolism and pharmacokinetic profiles of natural products from medicinal plants in the Congo basin.Chemical philanthropy: a path forward for antibiotic discovery?Exploration of Scaffolds from Natural Products with Antiplasmodial Activities, Currently Registered Antimalarial Drugs and Public Malarial Screen Data.To screen or not to screen: an impassioned plea for smarter chemical libraries to improve drug lead finding.A call for using natural compounds in the development of new antimalarial treatments - an introduction.Sequential transformations to access polycyclic chemotypes: asymmetric crotylation and metal carbenoid reactions.Branching cascades: a concise synthetic strategy targeting diverse and complex molecular frameworks.Scaffold diversity of exemplified medicinal chemistry space.Biology-oriented synthesis.Skeletal diversity via cationic rearrangements of substituted dihydropyrans.Design and synthesis of screening libraries based on the muurolane natural product scaffold.The spinosyn family of insecticides: realizing the potential of natural products research.Library construction and biological evaluation of enmein-type diterpenoid analogues as potential anticancer agents.Finding novel pharmaceuticals in the systems biology era using multiple effective drug targets, phenotypic screening and knowledge of transporters: where drug discovery went wrong and how to fix it.Druggable chemical space and enumerative combinatorics.Electrophile induced branching cascade: a powerful approach to access various molecular scaffolds and their exploration as novel anti-mycobacterial agents.Yeast synthetic biology platform generates novel chemical structures as scaffolds for drug discovery.Exopolysaccharides produced by marine bacteria and their applications as glycosaminoglycan-like moleculesBack to the Roots: Prediction of Biologically Active Natural Products from Ayurveda Traditional Medicine.Rapid and efficient access to secondary arylmethylamines.Charting Biologically Relevant Spirocyclic Compound Space.Recent derivatives from smaller classes of fermentation-derived antibacterials.From natural product-inspired pyrrolidine scaffolds to the development of new human Golgi α-mannosidase II inhibitors.Design and synthesis of analogues of natural products.Rule-Based Classification of Chemical Structures by Scaffold.Scaffold Diversity Synthesis and Its Application in Probe and Drug Discovery.Network pharmacology study on the mechanism of traditional Chinese medicine for upper respiratory tract infection.Probing the influence of an allylic methyl group in zearalenone analogues on binding to Hsp90.Chemoselective enrichment for natural products discovery.Relay catalytic branching cascade: a technique to access diverse molecular scaffolds.Oxygen-containing fragments in natural products.Strategies to diversify natural products for drug discovery.Engaging Allene-Derived Zwitterions in an Unprecedented Mode of Asymmetric [3+2]-Annulation Reaction.
P2860
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P2860
Scaffold diversity of natural products: inspiration for combinatorial library design.
description
2008 nî lūn-bûn
@nan
2008 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Scaffold diversity of natural products: inspiration for combinatorial library design.
@ast
Scaffold diversity of natural products: inspiration for combinatorial library design.
@en
type
label
Scaffold diversity of natural products: inspiration for combinatorial library design.
@ast
Scaffold diversity of natural products: inspiration for combinatorial library design.
@en
prefLabel
Scaffold diversity of natural products: inspiration for combinatorial library design.
@ast
Scaffold diversity of natural products: inspiration for combinatorial library design.
@en
P2860
P356
P1476
Scaffold diversity of natural products: inspiration for combinatorial library design.
@en
P2093
Kristina Grabowski
P2860
P304
P356
10.1039/B715668P
P577
2008-07-07T00:00:00Z