Evolution of the aging brain transcriptome and synaptic regulation - Wikidata - wikimedia - TriplyDB

Evolution of the aging brain transcriptome and synaptic regulation

Evolution of the aging brain transcriptome and synaptic regulation

http://www.wikidata.org/entity/Q33373343

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Apolipoprotein D: an overview of its role in aging and age-related diseases Preclinical Magnetic Resonance Imaging and Spectroscopy Studies of Memory, Aging, and Cognitive Decline Age-associated Cognitive Decline: Insights into Molecular Switches and Recovery Avenues NMDA Receptor Function During Senescence: Implication on Cognitive Performance Improving the predictive value of interventional animal models data REST and stress resistance in ageing and Alzheimer's disease KCNE2 forms potassium channels with KCNA3 and KCNQ1 in the choroid plexus epithelium A chaperome subnetwork safeguards proteostasis in aging and neurodegenerative disease Lipid-binding properties of human ApoD and Lazarillo-related lipocalins: functional implications for cell differentiation.Therapeutics for cognitive aging Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us?Mitochondrial permeability transition pore regulates Parkinson's disease development in mutant α-synuclein transgenic mice.Control of metabolic homeostasis by stress signaling is mediated by the lipocalin NLaz.A cross-laboratory comparison of expression profiling data from normal human postmortem brain.Transcriptomic evidence of a para-inflammatory state in the middle aged lumbar spinal cord.Distinct transcriptome expression of the temporal cortex of the primate Microcebus murinus during brain aging versus Alzheimer's disease-like pathology.Alzheimer's disease and neuronal network activity Age-Related Gene Expression in the Frontal Cortex Suggests Synaptic Function Changes in Specific Inhibitory Neuron Subtypes.Minimal peroxide exposure of neuronal cells induces multifaceted adaptive responses Homeostatic disinhibition in the aging brain and Alzheimer's disease Coordination of gene expression of arachidonic and docosahexaenoic acid cascade enzymes during human brain development and aging.NRF2 deficiency replicates transcriptomic changes in Alzheimer's patients and worsens APP and TAU pathology.Isoprenoids, small GTPases and Alzheimer's disease.Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease.MicroRNA, mRNA, and protein expression link development and aging in human and macaque brain Neurotoxic mechanisms of DNA damage: focus on transcriptional inhibition.The aging stress response.Probing the biology of Alzheimer's disease in mice.The biochemical aftermath of anti-amyloid immunotherapy.Age-related increases in right frontal activation during task switching are mediated by reaction time and white matter microstructure Neurogenetic effects on cognition in aging brains: a window of opportunity for intervention?Coordinated gene expression of neuroinflammatory and cell signaling markers in dorsolateral prefrontal cortex during human brain development and aging.Estrogen Effects on Cognitive and Synaptic Health Over the Lifecourse Disrupted energy metabolism and neuronal circuit dysfunction in cognitive impairment and Alzheimer's disease.Molecular changes in brain aging and Alzheimer's disease are mirrored in experimentally silenced cortical neuron networks.Accurate quantification of more than 4000 mouse tissue proteins reveals minimal proteome changes during aging.Reduced frontal cortex efficiency is associated with lower white matter integrity in aging.Glial β-oxidation regulates Drosophila energy metabolism.Analysis of nonlinear gene expression progression reveals extensive pathway and age-specific transitions in aging human brains Lifelong expression of apolipoprotein D in the human brainstem: correlation with reduced age-related neurodegeneration

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Evolution of the aging brain transcriptome and synaptic regulation

http://www.wikidata.org/entity/Q33373343

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2008年論文

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Evolution of the aging brain transcriptome and synaptic regulation

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Evolution of the aging brain transcriptome and synaptic regulation

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Evolution of the aging brain transcriptome and synaptic regulation

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Adrian Isaacs

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Bruce A Yankner

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Cheng Li

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Chengiz Geula

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Dana H Gabuzda

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James M Vann

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Jianbin Wang

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Kelly A Dakin

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Patrick M Loerch

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Tao Lu

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Initial sequencing and analysis of the human genome

Aging and gene expression in the primate brain

The Sequence of the Human Genome

Evolutionary and Biomedical Insights from the Rhesus Macaque Genome

Initial sequencing and comparative analysis of the mouse genome

The effects of aging on gene expression in the hypothalamus and cortex of mice

Basic local alignment search tool

Genome-wide atlas of gene expression in the adult mouse brain

Model-based analysis of oligonucleotide arrays: expression index computation and outlier detection

Impaired synaptic plasticity and cAMP response element-binding protein activation in Ca2+/calmodulin-dependent protein kinase type IV/Gr-deficient mice

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