Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report.
about
Exciting new advances in neuro-oncology: the avenue to a cure for malignant gliomaNoninvasive detection of temozolomide in brain tumor xenografts by magnetic resonance spectroscopy.Phase I trial of temozolomide plus O6-benzylguanine 5-day regimen with recurrent malignant glioma.Phase II study of irinotecan in combination with temozolomide (TEMIRI) in children with recurrent or refractory medulloblastoma: a joint ITCC and SIOPE brain tumor studyAn operational perspective of challenging statistical dogma while establishing a modern, secure distributed data management and imaging transport system: the Pediatric Brain Tumor Consortium phase I experience.Central nervous system penetration and enhancement of temozolomide activity in childhood medulloblastoma models by poly(ADP-ribose) polymerase inhibitor AG-014699.Efficient and stable MGMT-mediated selection of long-term repopulating stem cells in nonhuman primates.Adaptive dose-finding studies: a review of model-guided phase I clinical trials.Critical appraisal of temozolomide formulations in the treatment of primary brain tumors: patient considerationsThe use and effectiveness of temozolomide in children with central nervous system tumours: a survey from the Canadian Paediatric Brain Tumour ConsortiumTemozolomide in the treatment of children with newly diagnosed diffuse intrinsic pontine gliomas: a report from the Children's Oncology Group.Humanized bone marrow mouse model as a preclinical tool to assess therapy-mediated hematotoxicity.Management of high-grade gliomas in the pediatric patient: Past, present, and future.PI-3K Inhibitors Preferentially Target CD15+ Cancer Stem Cell Population in SHH Driven Medulloblastoma.Molecular profiling of childhood cancer: Biomarkers and novel therapiesMismatch repair deficiency: a temozolomide resistance factor in medulloblastoma cell lines that is uncommon in primary medulloblastoma tumours.A phase II study of O6-benzylguanine and temozolomide in pediatric patients with recurrent or progressive high-grade gliomas and brainstem gliomas: a Pediatric Brain Tumor Consortium study.Extended survival of glioblastoma patients after chemoprotective HSC gene therapySubstitution of aminomethyl at the meta-position enhances the inactivation of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.Diffuse brainstem gliomas in children: should we or shouldn't we biopsy?Bone marrow transplantation for severe aplastic anemia secondary to temozolomide.Treatment of high-grade glioma in children and adolescents.The adolescent and young adult with cancer: state of the art--brain tumor.A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.A simulation-based comparison of the traditional method, Rolling-6 design and a frequentist version of the continual reassessment method with special attention to trial duration in pediatric Phase I oncology trials.Temozolomide-mediated DNA methylation in human myeloid precursor cells: differential involvement of intrinsic and extrinsic apoptotic pathways.A Phase 1 Trial of TPI 287 as a Single Agent and in Combination With Temozolomide in Patients with Refractory or Recurrent Neuroblastoma or Medulloblastoma.Medulloblastoma in children and adolescents: a systematic review of contemporary phase I and II clinical trials and biology update.
P2860
Q24632791-606DF7DD-D8D2-4B14-A20D-B3890E7C0D86Q30496613-8D33DDA1-2DD9-4FCC-BBFC-DFA0ACF17389Q33383721-CA1DF849-3B50-46ED-8884-5B3855FC7009Q33409117-5D487D00-4AAB-4BEA-8323-4A25EEE5EB36Q33571622-5D67BB22-F75B-4728-8F2C-4DC993C3B675Q33729396-69EF0233-938F-4691-A2C3-A233533D9C3DQ33968014-4220B4B1-6806-4C61-BE80-29F585F17C1FQ34001009-37A196B8-6FBD-472C-A9C4-758E10DE78DBQ34418437-A26F2293-5153-4BB2-99EF-B6420E193707Q34541456-35E250A2-E8BC-4E77-A417-77C0BAA75186Q34722864-6AE5251B-6C23-480F-922F-EE87B100BD0FQ34810016-B0B1C771-2175-403C-858D-0B4FAB9DA1F8Q35206259-C0E5CB48-82F5-41A2-975A-AC6FCE0BE81DQ35944343-2D2D4C0B-16B0-4E08-9909-410DC82CDD59Q36250783-3B9C14AB-8A09-47B4-B13E-E97467F3ED16Q36387895-9E3C058B-4780-48A5-B552-6F5C8C3B9969Q36455403-781117E9-7161-4361-B0AD-E965540AB2CEQ36834118-3AD29FFD-8E35-4B9D-B569-14DC2772C130Q37105014-A3481EB8-1E01-47F3-B58F-421C6BBC0ED0Q37328146-55E0FE8D-D389-4C19-BEB2-03F8664D1083Q37330813-F9670B12-238B-4D00-8974-09677A3BC8ACQ37904503-D225925F-A1C3-4A32-9CF6-7D6527C12BCDQ38112071-914978B3-862A-4911-97EF-8D466DBE092BQ38961012-A15B57E9-7B4C-45FB-922A-B1E93ED0F7D0Q40313777-5069C622-5E15-472D-99C3-5C1B82D4ED84Q43092195-40CC0BE5-1D5F-4A67-A798-3E73643D1430Q46188537-6512ADFE-E8AC-423B-B88B-297B6D40BB9BQ47133403-F1967915-D68B-441D-B909-7DAE17F67A76
P2860
Phase I trial of single-dose temozolomide and continuous administration of o6-benzylguanine in children with brain tumors: a pediatric brain tumor consortium report.
description
2007 nî lūn-bûn
@nan
2007 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Phase I trial of single-dose t ...... brain tumor consortium report.
@ast
Phase I trial of single-dose t ...... brain tumor consortium report.
@en
type
label
Phase I trial of single-dose t ...... brain tumor consortium report.
@ast
Phase I trial of single-dose t ...... brain tumor consortium report.
@en
prefLabel
Phase I trial of single-dose t ...... brain tumor consortium report.
@ast
Phase I trial of single-dose t ...... brain tumor consortium report.
@en
P2093
P50
P1476
Phase I trial of single-dose t ...... brain tumor consortium report.
@en
P2093
Amar Gajjar
Clinton F Stewart
Dana Wallace
James M Boyett
Larry E Kun
Mary K Danks
Roger J Packer
Stewart Goldman
Tina Y Poussaint
Tobey J MacDonald
P304
P356
10.1158/1078-0432.CCR-07-1016
P407
P433
P577
2007-11-01T00:00:00Z