Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus
about
Signaling pathways in the molecular pathogenesis of adenocarcinomas of the esophagus and gastroesophageal junctionOrganization, evolution and functions of the human and mouse Ly6/uPAR family genesSquamous cell carcinoma antigen (SCCA) is up-regulated during Barrett's carcinogenesis and predicts esophageal adenocarcinoma resistance to neoadjuvant chemotherapyUpregulation of mucin glycoprotein MUC1 in the progression to esophageal adenocarcinoma and therapeutic potential with a targeted photoactive antibody-drug conjugateEctopic Cdx2 expression in murine esophagus models an intermediate stage in the emergence of Barrett's esophagus.Whole genome expression array profiling highlights differences in mucosal defense genes in Barrett's esophagus and esophageal adenocarcinomaIsolation and characterization of mouse and human esophageal epithelial cells in 3D organotypic culture.Modeling human gastrointestinal inflammatory diseases using microphysiological culture systems.Germline mutations in MSR1, ASCC1, and CTHRC1 in patients with Barrett esophagus and esophageal adenocarcinoma.Residual embryonic cells as precursors of a Barrett's-like metaplasia.Association between circulating levels of sex steroid hormones and Barrett's esophagus in men: a case-control analysis.Global changes in gene expression of Barrett's esophagus compared to normal squamous esophagus and gastric cardia tissues.Review: Experimental models for Barrett's esophagus and esophageal adenocarcinomaCox2 and β-catenin/T-cell factor signaling intestinalize human esophageal keratinocytes when cultured under organotypic conditionsBarrett esophagus: history, definition and etiopathogenyPleiotropic functions of EAPII/TTRAP/TDP2: cancer development, chemoresistance and beyondIn vitro model for studying esophageal epithelial differentiation and allergic inflammatory responses identifies keratin involvement in eosinophilic esophagitis.Barrett's Esophagus: Emerging Knowledge and Management StrategiesCYR61 and TAZ Upregulation and Focal Epithelial to Mesenchymal Transition May Be Early Predictors of Barrett's Esophagus Malignant Progression.Inhibition of Notch signaling enhances transdifferentiation of the esophageal squamous epithelium towards a Barrett's-like metaplasia via KLF4.SOX15 governs transcription in human stratified epithelia and a subset of esophageal adenocarcinomasCorneal Expression of SLURP-1 by Age, Sex, Genetic Strain, and Ocular Surface Health.Mutational spectrum of Barrett's stem cells suggests paths to initiation of a precancerous lesionGenome-wide profiling of DNA methylation and gene expression in esophageal squamous cell carcinomaNew models of neoplastic progression in Barrett's oesophagus.Cdx genes, inflammation, and the pathogenesis of intestinal metaplasia.Barrett's esophagus: genetic and cell changes.Mechanisms of Barrett's oesophagus: intestinal differentiation, stem cells, and tissue models.Molecular pathogenesis of human prostate basal cell hyperplasia.Transdifferentiation Requires iNOS Activation: Role of RING1A S-Nitrosylation.Goblet Cell Ratio in Combination with Differentiation and Stem Cell Markers in Barrett Esophagus Allow Distinction of Patients with and without Esophageal Adenocarcinoma.Differential protein expression and oncogenic gene network link tyrosine kinase ephrin B4 receptor to aggressive gastric and gastroesophageal junction cancers.Autophagy levels are elevated in barrett's esophagus and promote cell survival from acid and oxidative stress.Pathway Cross-Talk Analysis in Detecting Significant Pathways in Barrett's Esophagus Patients.Transcommitment: Paving the Way to Barrett's Metaplasia.The RNA editing enzyme APOBEC1 induces somatic mutations and a compatible mutational signature is present in esophageal adenocarcinomas.Math1/Atoh1 contributes to intestinalization of esophageal keratinocytes by inducing the expression of Muc2 and Keratin-20.CDX2 hox gene product in a rat model of esophageal cancerSox9 drives columnar differentiation of esophageal squamous epithelium: a possible role in the pathogenesis of Barrett's esophagus.Risk prediction in Barrett's esophagus - aspects of a combination of molecular and epidemiologic biomarkers reflecting alterations of the microenvironment.
P2860
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P2860
Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年学术文章
@wuu
2008年学术文章
@zh-cn
2008年学术文章
@zh-hans
2008年学术文章
@zh-my
2008年学术文章
@zh-sg
2008年學術文章
@yue
name
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@ast
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@en
type
label
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@ast
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@en
prefLabel
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@ast
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@en
P2093
P2860
P1433
P1476
Cdx1 and c-Myc foster the init ...... ium toward Barrett's esophagus
@en
P2093
Andres Klein-Szanto
Anil K Rustgi
Debra G Silberg
Douglas B Stairs
Hiroshi Nakagawa
John P Lynch
John W Tobias
Shukriyyah D Mitchell
P2860
P356
10.1371/JOURNAL.PONE.0003534
P407
P577
2008-10-27T00:00:00Z