REST regulates distinct transcriptional networks in embryonic and neural stem cells.
about
A genome-wide screen for genetic variants that modify the recruitment of REST to its target genesMicrocephaly gene links trithorax and REST/NRSF to control neural stem cell proliferation and differentiationThe Transcription Repressor REST in Adult Neurons: Physiology, Pathology, and Diseases(1,2,3)Expression and function of the dense-core vesicle membranes are governed by the transcription repressor RESTA key role for poly(ADP-ribose) polymerase 3 in ectodermal specification and neural crest developmentEvidence-Based Theory for Integrated Genome Regulation of Ontogeny--An Unprecedented Role of Nuclear FGFR1 SignalingNuclear localization of Prickle2 is required to establish cell polarity during early mouse embryogenesisHuman accelerated region 1 noncoding RNA is repressed by REST in Huntington's diseaseREST is a hypoxia-responsive transcriptional repressorDynamic status of REST in the mouse ESC pluripotency networkKinetic analysis of npBAF to nBAF switching reveals exchange of SS18 with CREST and integration with neural developmental pathwaysRegulated expression of the Ras effector Rin1 in forebrain neuronsStem cells have different needs for RESTChIP-Seq Data Mining: Remarkable Differences in NRSF/REST Target Genes between Human ESC and ESC-Derived NeuronsREST and CoREST modulate neuronal subtype specification, maturation and maintenance.Differential deployment of REST and CoREST promotes glial subtype specification and oligodendrocyte lineage maturation.An epigenetic signature in peripheral blood predicts active ovarian cancerThe transcription factor REST is lost in aggressive breast cancer.Comparison of REST cistromes across human cell types reveals common and context-specific functionsMediator and human diseaseChromatin properties of regulatory DNA probed by manipulation of transcription factors.REST interacts with Cbx proteins and regulates polycomb repressive complex 1 occupancy at RE1 elementsModeling of epigenome dynamics identifies transcription factors that mediate Polycomb targeting.A decade of systems biologyCorepressor for element-1-silencing transcription factor preferentially mediates gene networks underlying neural stem cell fate decisions.Toward a complete in silico, multi-layered embryonic stem cell regulatory network.Specification of skeletal muscle differentiation by repressor element-1 silencing transcription factor (REST)-regulated Kv7.4 potassium channels.A REST derived gene signature stratifies glioblastomas into chemotherapy resistant and responsive diseaseREST and CoREST are transcriptional and epigenetic regulators of seminal neural fate decisions.An RNA binding protein promotes axonal integrity in peripheral neurons by destabilizing REST.Neural stem cell differentiation is dictated by distinct actions of nuclear receptor corepressors and histone deacetylases.High throughput screening for inhibitors of REST in neural derivatives of human embryonic stem cells reveals a chemical compound that promotes expression of neuronal genes.Regulation of neural macroRNAs by the transcriptional repressor REST.Interplay of chemical neurotransmitters regulates developmental increase in electrical synapses.TACO: a general-purpose tool for predicting cell-type-specific transcription factor dimers.Coassembly of REST and its cofactors at sites of gene repression in embryonic stem cells.A comparison of the rest complex binding patterns in embryonic stem cells and epiblast stem cells.Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype.Borna disease virus phosphoprotein impairs the developmental program controlling neurogenesis and reduces human GABAergic neurogenesis.AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells.
P2860
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P2860
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
description
2008 nî lūn-bûn
@nan
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@ast
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@en
type
label
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@ast
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@en
prefLabel
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@ast
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@en
P2093
P2860
P50
P1433
P1476
REST regulates distinct transcriptional networks in embryonic and neural stem cells.
@en
P2093
Chia-lin Wei
Christina Hui-leng Teh
Galih Kunarso
Gopalan Srinivasan
Kee Yew Wong
Lawrence W Stanton
Leonard Lipovich
Megan L Cooper
R Krishna Murthy Karuturi
Rory Johnson
P2860
P356
10.1371/JOURNAL.PBIO.0060256
P407
P577
2008-10-01T00:00:00Z