Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine - Wikidata - wikimedia - TriplyDB

Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine

Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine

http://www.wikidata.org/entity/Q33380531

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Pharmacogenomics and personalized medicine: a review focused on their application in the Chinese population Association between thiopurine S-methyltransferase polymorphisms and thiopurine-induced adverse drug reactions in patients with inflammatory bowel disease: a meta-analysis Model-Based Individualized Treatment of Chemotherapeutics: Bayesian Population Modeling and Dose Optimization A study to explore the correlation of ABCB1, ABCG2, OCT1 genetic polymorphisms and trough level concentration with imatinib mesylate-induced thrombocytopenia in chronic myeloid leukemia patients.Use of thiopurines in inflammatory bowel disease: Safety issues.Thiopurine pharmacogenomics: association of SNPs with clinical response and functional validation of candidate genes.Association of ITPA genotype with event-free survival and relapse rates in children with acute lymphoblastic leukemia undergoing maintenance therapy Determinants of mercaptopurine toxicity in paediatric acute lymphoblastic leukemia maintenance therapy Optimal chemotherapy for leukemia: a model-based strategy for individualized treatment.The increasing complexity of mercaptopurine pharmacogenomics.Are patients with intermediate TPMT activity at increased risk of myelosuppression when taking thiopurine medications?Pharmacogenomics in the treatment of inflammatory bowel disease.Inosine triphosphate pyrophosphatase 94C>A polymorphism: clinical implications for patients with systemic lupus erythematosus treated with azathioprine.Thiopurine S-methyltransferase polymorphisms and thiopurine toxicity in treatment of inflammatory bowel disease.Optimizing thiopurine therapy in inflammatory bowel disease.Therapeutic drug monitoring in cancer chemotherapy.Availability of pharmacogenetic and pharmacogenomic information in anticancer drug monographs in France: personalized cancer therapy.Pharmacogenetics and individualized therapy in children: immunosuppressants, antidepressants, anticancer and anti-inflammatory drugs.Pharmacogenetic determinants of mercaptopurine disposition in children with acute lymphoblastic leukemia.Impact of genetic polymorphisms on chemotherapy toxicity in childhood acute lymphoblastic leukemia.Pharmacogenetic considerations for acute lymphoblastic leukemia therapies.Review article: recent advances in pharmacogenetics and pharmacokinetics for safe and effective thiopurine therapy in inflammatory bowel disease.Identification of Potential Anticancer Activities of Novel Ganoderma lucidum Extracts Using Gene Expression and Pathway Network Analysis.Genetic variants in 6-mercaptopurine pathway as potential factors of hematological toxicity in acute lymphoblastic leukemia patients.A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs.Gene polymorphisms involved in manifestation of leucopenia, digestive intolerance, and pancreatitis in azathioprine-treated patients.Pro32Thr polymorphism of inosine triphosphate pyrophosphatase gene predicts efficacy of low-dose azathioprine for patients with systemic lupus erythematosus.Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL.High frequency of mutant thiopurine S-methyltransferase genotypes in Mexican patients with systemic lupus erythematosus and rheumatoid arthritis.Influences of XDH genotype by gene-gene interactions with SUCLA2 for thiopurine-induced leukopenia in Korean patients with Crohn's disease.Influence of SLCO1B1 polymorphism on maintenance therapy for childhood leukemia.Optimal predictor for 6-mercaptopurine intolerance in Chinese children with acute lymphoblastic leukemia: NUDT15, TPMT, or ITPA genetic variants?Imidazoles as potential anticancer agents

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P2860

Pharmacogenomic studies of the anticancer and immunosuppressive thiopurines mercaptopurine and azathioprine

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British Journal of Clinical Pharmacology

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Pharmacogenomic studies of the ...... ercaptopurine and azathioprine

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P2860

Molecular diagnosis of thiopurine S-methyltransferase deficiency: genetic basis for azathioprine and mercaptopurine intolerance

Therapeutic drug monitoring of cytotoxic drugs

New developments in the immunosuppressive drug monitoring of cyclosporine, tacrolimus, and azathioprine.

Genotypic analysis of thiopurine S-methyltransferase in patients with Crohn's disease and severe myelosuppression during azathioprine therapy.

Therapeutic drug monitoring of antimetabolic cytotoxic drugs.

Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency.

The clinical pharmacology of 6-mercaptopurine.

Mutation in the ITPA gene predicts intolerance to azathioprine.

Pharmacogenetics of cancer therapy: getting personal

The efficacy of azathioprine for the treatment of inflammatory bowel disease: a 30 year review.

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23132910

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pharmacogenomics

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