Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia. - Wikidata - wikimedia - TriplyDB

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

http://www.wikidata.org/entity/Q33386724

about

The contribution of mouse models to the understanding of constitutional thrombocytopenia Congenital amegakaryocytic thrombocytopenia.Inhibition of Thrombopoietin/Mpl Signaling in Adult Hematopoiesis Identifies New Candidates for Hematopoietic Stem Cell Maintenance.A hyperactive Mpl-based cell growth switch drives macrophage-associated erythropoiesis through an erythroid-megakaryocytic precursor.Generation and genetic modification of induced pluripotent stem cells.Alpharetroviral vectors: from a cancer-causing agent to a useful tool for human gene therapy.Hypoxia and cytokines regulate carbonic anhydrase 9 expression in hepatocellular carcinoma cells in vitro.Efficient in vivo regulation of cytidine deaminase expression in the haematopoietic system using a doxycycline-inducible lentiviral vector system.Cytological characterization of murine bone marrow and spleen hematopoietic compartments for improved assessment of toxicity in preclinical gene marking models.

P2860

Q26740409-15E8D696-69C6-47BA-89BD-BD364F8D3B1F Q33394248-EE0061C5-5FCB-47BE-84D0-F341367C1B94 Q33424158-EC737E2A-FC0E-4EB7-A810-792F4C3CA2A6 Q35056286-B80DF4A2-B7B5-4C8D-859C-0D61A081F1B6 Q37763190-4D95B6AA-5C82-4AA8-9773-6A730194F92F Q38285765-389C07BE-1F56-49E8-BD74-E8C5BFEDA486 Q39326693-9176726F-8249-41F0-A4CE-7EA031CFD381 Q39347244-DA873D0E-667B-4158-9F2D-53DE86D298C2 Q45397622-9846924A-9594-4CC2-AACB-2760792677FB

P2860

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

http://www.wikidata.org/entity/Q33386724

description

2009 nî lūn-bûn

@nan

2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@ast

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@en

type

label

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@ast

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@en

prefLabel

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@ast

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@en

P1433

Q33386724-A393E73A-4A09-4F91-8026-749632DA8920

P1476

Q33386724-2BF784B5-99C8-41DB-AD6E-F9530BF1C8F3

P2093

Q33386724-2D8C98CE-F7BB-446E-A458-6A88C0B8BB15

Q33386724-4EA25C46-D4F1-4D5A-B438-3FA95C725984

Q33386724-5C85801C-FD80-4366-8614-4377C66DE487

Q33386724-82B395C1-D13D-4F91-98E9-B1A4D6D032C8

Q33386724-965FD6F2-1F7C-4BE1-84E2-21FBAD43B7C0

Q33386724-B4617D3A-E033-4CEF-B497-0B486AF6A8C5

Q33386724-BE62B1D9-7781-4C79-90CD-182A877D99FC

Q33386724-D48C583F-ED76-4667-94CB-CB855F23C808

Q33386724-FC25D004-2B70-4784-8296-93DE71800DFC

Q33386724-FF5E0944-6586-4837-BE8F-2B3A731F47F4

P2860

Q33386724-06E9BE6B-39E1-4AA7-93F1-1BE7C28A1470

Q33386724-07AC3C62-4D8A-4092-8AE0-99C519DC17C6

Q33386724-0ABA00C6-41A6-4C06-8517-32C217D33D2F

Q33386724-0ACB2067-C313-427D-8D6C-0F4E49006E3C

Q33386724-0AE90A75-998A-4101-8E7A-8C53A7AAB8D1

Q33386724-16753B83-19BE-4F46-9D2D-D1EFAE23CEEC

Q33386724-2ABBA95F-AD4C-4608-83DA-A4E3D42944BA

Q33386724-31508ED7-230C-4010-B5F4-D1ABEB6F756F

Q33386724-38D9EA9C-15ED-4D2E-9F6B-EAF12B5A9EEC

Q33386724-3D2C46A9-38D2-4209-931B-DB3A291E663A

P304

Q33386724-4F41104F-7675-42F1-9CA7-35905B1A7D59

P31

Q33386724-C187E601-EA95-484D-A5CF-FC87481078B8

P356

Q33386724-46CE9666-9633-468F-A51D-13C69EE8F396

P433

Q33386724-048726CB-987D-4579-AB32-133FD3FA4FB8

P478

Q33386724-15F59A38-3559-4028-955B-892E5173973A

P577

Q33386724-426D7CF3-67B6-459E-9ED8-BC32E38092F7

P5875

Q33386724-5DA94A32-5D3C-4060-960C-E195BF4B311B

P698

Q33386724-A40DC413-C954-4B55-A572-5E1FB126AC86

P921

Q33386724-2CD2A3B1-E49F-4C74-B379-B96391B388A1

Q33386724-81F11EBB-81A2-46A6-9699-007ED316BD34

P932

Q33386724-5336E7E9-F596-46A8-9EBF-6D9AA93698AC

P356

P1433

Molecular Therapy

P1476

Gene therapy of MPL deficiency: challenging balance between leukemia and pancytopenia.

@en

P2093

Christopher Baum

http://www.w3.org/2001/XMLSchema#string

Daniel C Wicke

http://www.w3.org/2001/XMLSchema#string

Dirk Heckl

http://www.w3.org/2001/XMLSchema#string

Guntram Buesche

http://www.w3.org/2001/XMLSchema#string

Hans Kreipe

http://www.w3.org/2001/XMLSchema#string

Johann Meyer

http://www.w3.org/2001/XMLSchema#string

Karl H Welte

http://www.w3.org/2001/XMLSchema#string

Matthias Ballmaier

http://www.w3.org/2001/XMLSchema#string

Ute Modlich

http://www.w3.org/2001/XMLSchema#string

Zhixiong Li

http://www.w3.org/2001/XMLSchema#string

P2860

The molecular mechanisms that control thrombopoiesis

Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus

Molecular cloning and characterization of MPL, the human homolog of the v-mpl oncogene: identification of a member of the hematopoietic growth factor receptor superfamily

c-mpl mutations are the cause of congenital amegakaryocytic thrombocytopenia

A putative truncated cytokine receptor gene transduced by the myeloproliferative leukemia virus immortalizes hematopoietic progenitors

The c-Mpl ligand (thrombopoietin) stimulates tyrosine phosphorylation of Jak2, Shc, and c-Mpl

Incomplete restoration of Mpl expression in the mpl-/- mouse produces partial correction of the stem cell-repopulating defect and paradoxical thrombocytosis.

Congenital amegakaryocytic thrombocytopenia: a retrospective clinical analysis of 20 patients.

Megakaryocyte development and platelet production.

Evidence for long-term efficacy and safety of gene therapy for Wiskott-Aldrich syndrome in preclinical models.

P304

343-352

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/MT.2009.233

http://www.w3.org/2001/XMLSchema#string

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

18

http://www.w3.org/2001/XMLSchema#string

P577

2009-10-20T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

38025162

http://www.w3.org/2001/XMLSchema#string

P698

19844195

http://www.w3.org/2001/XMLSchema#string

P921

P932

2839299

http://www.w3.org/2001/XMLSchema#string