Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide.
about
Imaging radiation response in tumor and normal tissue.Biomarkers and molecular probes for cell death imaging and targeted therapeuticsPreclinical assessment of carboplatin treatment efficacy in lung cancer by 18F-ICMT-11-positron emission tomographyPositron emission tomography imaging of drug-induced tumor apoptosis with a caspase-3/7 specific [18F]-labeled isatin sulfonamide18F-labeling using click cycloadditions.The impact of click chemistry in medicinal chemistry.Synthesis and evaluation of isatin analogs as caspase-3 inhibitors: introduction of a hydrophilic group increases potency in a whole cell assay"Click"-capture, ring-opening metathesis polymerization (ROMP), release: facile triazolation utilizing ROMP-derived oligomeric phosphates.Development of radiotracers for oncology--the interface with pharmacologySmall Molecule Active Site Directed Tools for Studying Human CaspasesClick Reaction: An Applicable Radiolabeling Method for Molecular ImagingImaging caspase-3 activation as a marker of apoptosis-targeted treatment response in cancer.Managing lymphoma with non-FDG radiotracers: current clinical and preclinical applications.Rapid synthesis of the indole-indolone scaffold via [3+2] annulation of arynes by methyl indole-2-carboxylates.SPECT and PET radiopharmaceuticals for molecular imaging of apoptosis: from bench to clinicNew frontiers in the design and synthesis of imaging probes for PET oncology: current challenges and future directions.Isatin sulfonamides: potent caspases-3 and -7 inhibitors, and promising PET and SPECT radiotracers for apoptosis imaging.Computational studies on the regioselectivity of metal-catalyzed synthesis of 1,2,3 triazoles via click reaction: a review.Apoptosis imaging studies in various animal models using radio-iodinated peptide.18 F-Labeling of Sensitive Biomolecules for Positron Emission Tomography.Fluorinated isatin derivatives. Part 3. New side-chain fluoro-functionalized pyrrolidinyl sulfonyl isatins as potent caspase-3 and -7 inhibitors.The future of imaging: developing the tools for monitoring response to therapy in oncology: the 2009 Sir James MacKenzie Davidson Memorial lecture.Highly efficient click labeling using 2-[¹⁸F]fluoroethyl azide and synthesis of an ¹⁸FN-hydroxysuccinimide ester as conjugation agent.Direct access to triazole-olefins through catalytic cycloaddition of azides to unsaturated aldehydes.Chelator-accelerated one-pot 'click' labeling of small molecule tracers with 2-[¹⁸F]fluoroethyl azide.Evaluation of a 125I-labelled benzazepinone derived voltage-gated sodium channel blocker for imaging with SPECT.[18F]Fluoroalkyl azides for rapid radiolabeling and (Re)investigation of their potential towards in vivo click chemistry.A NHC-catalyzed 1,3-dipolar cycloaddition reaction of allyl ketones with azides: direct access to 1,4,5-trisubstituted 1,2,3-triazoles.The traceless Staudinger ligation for indirect 18F-radiolabelling.Copper-free click--a promising tool for pre-targeted PET imaging.Screening of bromotyramine analogues as antifouling compounds against marine bacteria.Radiolabeled apoptosis imaging agents for early detection of response to therapyClinical translation of [F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer
P2860
Q26798266-86DCC4C4-5C9B-4396-B709-F149AE25BF83Q26866387-FCB778A2-19C8-4D17-9A74-4BBF0449828EQ28540769-793442E8-839D-4FD9-930B-7406EA4084D8Q33508763-A96A3082-8251-4D13-A0DC-3FFE7B34BE1CQ33804911-DDFDD9DC-8067-4FA2-91A9-43DBFA743E32Q34274356-221105DD-7690-4D56-A521-CB348854452EQ34785375-F880419E-4D16-48F8-91FF-988C04FBBC3CQ34994936-D3BFE5A6-F94F-460C-B5BE-F47CE95CED70Q35195500-FA4E3CFE-215F-431A-9BBC-58331C1CB20EQ35836079-636D0B17-A493-4DEE-9254-FCC175628528Q36241255-CFFDDCBC-C4F2-4B9E-9589-F409C888B4D8Q36920403-945D1A1E-0C3D-4AD9-BC7E-22B98EA68EB2Q36948431-50435B39-5FA1-48D4-8F3C-1DF2BFE59B96Q37313261-8301148E-1EEE-4EC8-984C-DF92EEDCA586Q37746356-D13D3ECA-C209-4519-95C1-7B9C6BB60AE3Q38040666-7AB3B088-5752-4331-BFD0-6302E07FBC8CQ38541496-56A8403C-FB44-40E0-8EF2-F6BF4D98F48FQ38589426-29DF09ED-9900-4634-81AC-C086E57BEE5EQ38937295-F84E0DAC-1F0B-423B-A1CB-3EDF5467904EQ39432870-D3CA6F38-4BF0-4097-852B-1BAB4F6EE54CQ39959226-18392656-0F24-4497-814C-636B6E5B9D3FQ42419554-B544430D-226A-4ACA-A24C-3B0BD8D60A6FQ42430282-B9058ED7-4FA7-42B6-A32D-032FF13E167EQ44461813-D05B07FE-27F9-4CEE-8430-EE2FDD2C5A79Q44472120-C90257F7-89A2-413F-A45B-064DDA2E8595Q48311902-B90596A4-2E98-4F23-8042-20E3C4190D9DQ50545531-0D3FCCB2-82EF-4686-9781-069025196B3AQ50645803-84FFE5CF-28FF-4B8E-8C20-F12D99A365E7Q52712424-AD2589FC-D063-4D82-BAC2-8EF28A8698C3Q53186369-40F97229-E64E-41E1-80F8-19CBF0394DDAQ54578106-CBF796FE-A0B1-4A20-9BF1-A6EEF5AAAA0AQ59100768-2C8DD5B2-8795-4061-A49F-572AE29BF3D8Q59127014-C024EBFC-7856-4E6D-A37C-F14721A88DF8
P2860
Design, synthesis, and biological characterization of a caspase 3/7 selective isatin labeled with 2-[18F]fluoroethylazide.
description
2008 nî lūn-bûn
@nan
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@ast
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@en
type
label
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@ast
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@en
prefLabel
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@ast
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@en
P2093
P356
P1476
Design, synthesis, and biologi ...... with 2-[18F]fluoroethylazide.
@en
P2093
Eric O Aboagye
Erik Arstad
Matthias Glaser
Meg Perumal
Quang-De Nguyen
P304
P356
10.1021/JM801107U
P407
P50
P577
2008-12-01T00:00:00Z