Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions.
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Site-specific translocation and evidence of postnatal origin of the t(1;19) E2A-PBX1 fusion in childhood acute lymphoblastic leukemia.Semisynthetic combinatorial antibody libraries: a chemical solution to the diversity problemRheumatoid factors from the peripheral blood of two patients with rheumatoid arthritis are genetically heterogeneous and somatically mutatedFrequent N addition and clonal relatedness among immunoglobulin lambda light chains expressed in rheumatoid arthritis synovia and PBL, and the influence of V lambda gene segment utilization on CDR3 lengthClonally-related immunoglobulin VH domains and nonrandom use of DH gene segments in rheumatoid arthritis synoviumB cell receptor editing in tolerance and autoimmunitySelection of apoptotic cell specific human antibodies from adult bone marrowHematopoiesis in the equine fetal liver suggests immune preparedness.Human combinatorial antibody libraries to hepatitis B surface antigen.Immunoglobulin heavy chain gene expression in peripheral blood B lymphocytes.Human IgG Fc-binding phage antibodies constructed from synovial fluid CD38+ B cells of patients with rheumatoid arthritis show the imprints of an antigen-dependent process of somatic hypermutation and clonal selection.Identification of the V genes encoding xenoantibodies in non-immunosuppressed rhesus monkeys.Ordering human CD34+CD10-CD19+ pre/pro-B-cell and CD19- common lymphoid progenitor stages in two pro-B-cell development pathways.Autologous lymphoma vaccines induce human T cell responses against multiple, unique epitopes.Robust memory responses against influenza vaccination in pemphigus patients previously treated with rituximabBone marrow cells in X-linked agammaglobulinemia express pre-B-specific genes (lambda-like and V pre-B) and present immunoglobulin V-D-J gene usage strongly biased to a fetal-like repertoire.Repertoire of human antibodies against the polysaccharide capsule of Streptococcus pneumoniae serotype 6B.Clonal deletion of specific thymocytes by an immunoglobulin idiotype.Evidence of antigen receptor-influenced oligoclonal B lymphocyte expansion in the synovium of a patient with longstanding rheumatoid arthritis.Somatic diversification in the heavy chain variable region genes expressed by human autoantibodies bearing a lupus-associated nephritogenic anti-DNA idiotypeAntigen-specific B cell detection reagents: use and quality controlAnalysis of immunoglobulin transcripts and hypermutation following SHIV(AD8) infection and protein-plus-adjuvant immunizationCharacterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.Superantigen properties of a human sialoprotein involved in gut-associated immunity.Somatic mutation and CDR3 lengths of immunoglobulin kappa light chains expressed in patients with rheumatoid arthritis and in normal individualsRecognition by recombinant autoimmune thyroid disease-derived Fab fragments of a dominant conformational epitope on human thyroid peroxidase.Use of D gene segments with irregular spacers in terminal deoxynucleotidyltransferase (TdT)+/+ and TdT-/- mice carrying a human Ig heavy chain transgenic minilocus.Hodgkin disease: Hodgkin and Reed-Sternberg cells picked from histological sections show clonal immunoglobulin gene rearrangements and appear to be derived from B cells at various stages of developmentA transgenic mouse that expresses a diversity of human sequence heavy and light chain immunoglobulinsGenetic analysis of self-associating immunoglobulin G rheumatoid factors from two rheumatoid synovia implicates an antigen-driven responsePredominance of fetal type DJH joining in young children with B precursor lymphoblastic leukemia as evidence for an in utero transforming event.Human immunoglobulin heavy-chain minilocus recombination in transgenic mice: gene-segment use in mu and gamma transcripts.Clonal analysis of a human antibody response. II. Sequences of the VH genes of human IgM, IgG, and IgA to rabies virus reveal preferential utilization of VHIII segments and somatic hypermutationHigh-frequency representation of a single VH gene in the expressed human B cell repertoireSomatic variation precedes extensive diversification of germline sequences and combinatorial joining in the evolution of immunoglobulin heavy chain diversity.Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome.Natural and man-made V-gene repertoires for antibody discovery.Genetic analysis of the variable region genes encoding a monospecific human natural anti-DNA antibody.Repertoire cloning of lupus anti-DNA autoantibodies.Long-lived antigen-induced IgM plasma cells demonstrate somatic mutations and contribute to long-term protection.
P2860
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P2860
Multiple mechanisms participate in the generation of diversity of human H chain CDR3 regions.
description
1991 nî lūn-bûn
@nan
1991 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1991 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
1991年の論文
@ja
1991年論文
@yue
1991年論文
@zh-hant
1991年論文
@zh-hk
1991年論文
@zh-mo
1991年論文
@zh-tw
1991年论文
@wuu
name
Multiple mechanisms participat ...... of human H chain CDR3 regions.
@ast
Multiple mechanisms participat ...... of human H chain CDR3 regions.
@en
type
label
Multiple mechanisms participat ...... of human H chain CDR3 regions.
@ast
Multiple mechanisms participat ...... of human H chain CDR3 regions.
@en
prefLabel
Multiple mechanisms participat ...... of human H chain CDR3 regions.
@ast
Multiple mechanisms participat ...... of human H chain CDR3 regions.
@en
P1476
Multiple mechanisms participat ...... of human H chain CDR3 regions
@en
P2093
P304
P407
P577
1991-09-01T00:00:00Z