A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation - Wikidata - wikimedia - TriplyDB

A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation

A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation

http://www.wikidata.org/entity/Q33394515

about

Ubiquitin-dependent proteasomal degradation of human liver cytochrome P450 2E1: identification of sites targeted for phosphorylation and ubiquitination RNAi-based screening identifies kinases interfering with dioxin-mediated up-regulation of CYP1A1 activity Multisite phosphorylation of human liver cytochrome P450 3A4 enhances Its gp78- and CHIP-mediated ubiquitination: a pivotal role of its Ser-478 residue in the gp78-catalyzed reaction.Liver cytochrome P450 3A ubiquitination in vivo by gp78/autocrine motility factor receptor and C terminus of Hsp70-interacting protein (CHIP) E3 ubiquitin ligases: physiological and pharmacological relevance.Liver cytochrome P450 3A endoplasmic reticulum-associated degradation: a major role for the p97 AAA ATPase in cytochrome P450 3A extraction into the cytosol.CHIP and gp78-mediated ubiquitination of CYP3A4: Implications for the pharmacology of anticancer agents.Human liver cytochrome P450 3A4 ubiquitination: molecular recognition by UBC7-gp78 autocrine motility factor receptor and UbcH5a-CHIP-Hsc70-Hsp40 E2-E3 ubiquitin ligase complexes The Localization of Cytochrome P450s CYP1A1 and CYP1A2 into Different Lipid Microdomains Is Governed by Their N-terminal and Internal Protein Regions.Unusual properties of the cytochrome P450 superfamily.The sequence and analysis of a Chinese pig genome Long-term virus-induced alterations of CYP3A-mediated drug metabolism: a look at the virology, immunology and molecular biology of a multi-faceted problem.Hepatic cytochrome P450 ubiquitination: conformational phosphodegrons for E2/E3 recognition?Marking the tempo for myogenesis: Pax7 and the regulation of muscle stem cell fate decisions Acetaminophen induces accumulation of functional rat CYP3A via polyubiquitination dysfunction.Impact of physiological, pathological and environmental factors on the expression and activity of human cytochrome P450 2D6 and implications in precision medicine.Post-translational dual regulation of cytochrome P450 aromatase at the catalytic and protein levels by phosphorylation/dephosphorylation.Membrane Protein Quantity Control at the Endoplasmic Reticulum.Regulation of diacylglycerol acyltransferase 2 protein stability by gp78-associated endoplasmic-reticulum-associated degradation.Hepatic cytochromes P450: structural degrons and barcodes, posttranslational modifications and cellular adapters in the ERAD-endgame.Co-culture with mesenchymal stem cells enhances metabolic functions of liver cells in bioartificial liver system.

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P2860

A role for protein phosphorylation in cytochrome P450 3A4 ubiquitin-dependent proteasomal degradation

http://www.wikidata.org/entity/Q33394515

description

2008 nî lūn-bûn

@nan

2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

@ja

2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

@zh-mo

2008年論文

@zh-tw

2008年论文

@wuu

name

A role for protein phosphoryla ...... endent proteasomal degradation

@ast

A role for protein phosphoryla ...... endent proteasomal degradation

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type

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A role for protein phosphoryla ...... endent proteasomal degradation

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A role for protein phosphoryla ...... endent proteasomal degradation

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A role for protein phosphoryla ...... endent proteasomal degradation

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A role for protein phosphoryla ...... endent proteasomal degradation

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Journal of Biological Chemistry

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A role for protein phosphoryla ...... endent proteasomal degradation

@en

P2093

Andrew N Krutchinsky

http://www.w3.org/2001/XMLSchema#string

Changhui Deng

http://www.w3.org/2001/XMLSchema#string

Maria Almira Correia

http://www.w3.org/2001/XMLSchema#string

Mingxiang Liao

http://www.w3.org/2001/XMLSchema#string

Nicholas Hoe

http://www.w3.org/2001/XMLSchema#string

Poulomi Acharya

http://www.w3.org/2001/XMLSchema#string

Yongqiang Wang

http://www.w3.org/2001/XMLSchema#string

P2860

The kinase DYRK phosphorylates protein-synthesis initiation factor eIF2Bepsilon at Ser539 and the microtubule-associated protein tau at Thr212: potential role for DYRK as a glycogen synthase kinase 3-priming kinase

The tumor autocrine motility factor receptor, gp78, is a ubiquitin protein ligase implicated in degradation from the endoplasmic reticulum

Human HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulum

CYP3A4 ubiquitination by gp78 (the tumor autocrine motility factor receptor, AMFR) and CHIP E3 ligases

Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha

The activity of a human endoplasmic reticulum-associated degradation E3, gp78, requires its Cue domain, RING finger, and an E2-binding site

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

A complex of Cdc4p, Skp1p, and Cdc53p/cullin catalyzes ubiquitination of the phosphorylated CDK inhibitor Sic1p.

CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival

Roles of molecular chaperones in endoplasmic reticulum (ER) quality control and ER-associated degradation (ERAD)

P304

5671-5684

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scholarly article

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10.1074/JBC.M806104200

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9

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284

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P577

2008-12-18T00:00:00Z

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19095658

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phosphorylation

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2645824

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