Low-avidity anti-HPA-1a alloantibodies are capable of antigen-positive platelet destruction in the NOD/SCID mouse model of alloimmune thrombocytopenia.
about
Autoantibody-mediated complement activation on platelets is a common finding in patients with immune thrombocytopenic purpura (ITP).A point mutation in the EGF-4 domain of β(3) integrin is responsible for the formation of the Sec(a) platelet alloantigen and affects receptor functionA novel assay for the detection of anti-human platelet antigen antibodies (HPA-1a) based on peptide aptamer technology.Prevalence and clinical significance of low-avidity HPA-1a antibodies in women exposed to HPA-1a during pregnancy.The implementation of surface plasmon resonance technique in monitoring pregnancies with expected fetal and neonatal alloimmune thrombocytopenia.Neonatal alloimmune thrombocytopenia: pathogenesis, diagnosis and management.Inhibition of HPA-1a alloantibody-mediated platelet destruction by a deglycosylated anti-HPA-1a monoclonal antibody in mice: toward targeted treatment of fetal-alloimmune thrombocytopenia.Predicting risk severity and response of fetal neonatal alloimmune thrombocytopenia.Low-frequency human platelet antigens as triggers for neonatal alloimmune thrombocytopenia.Recommendations for the use of the non-obese diabetic/severe combined immunodeficiency mouse model in autoimmune and drug-induced thrombocytopenia: communication from the SSC of the ISTH.A multicenter validation of recombinant β3 integrin-coupled beads to detect human platelet antigen-1 alloantibodies in 498 cases of fetomaternal alloimmune thrombocytopenia.Recent progress in understanding the pathogenesis of fetal and neonatal alloimmune thrombocytopenia.Alloantibody against new platelet alloantigen (Lap(a)) on glycoprotein IIb is responsible for a case of fetal and neonatal alloimmune thrombocytopenia.Fetal and neonatal alloimmune thrombocytopenia: predictive factors of intracranial hemorrhage.The Elements Steering Pathogenesis in IgG-Mediated Alloimmune Diseases.Glycosylation pattern of anti-platelet IgG is stable during pregnancy and predicts clinical outcome in alloimmune thrombocytopenia.Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: a laboratory study using an in vitro model.External quality assessment in molecular immunohematology: the INSTAND proficiency test program.Molecular organization of various collagen fragments as revealed by atomic force microscopy and diffusion-ordered NMR spectroscopy.Assessment of human platelet survival in the NOD/SCID mouse model: technical considerations.Molecular and Functional Characterization of Fcγ Receptor IIIb-Ligand Interaction: Implications for Neutrophil-Mediated Immune Mechanisms in Malaria
P2860
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P2860
Low-avidity anti-HPA-1a alloantibodies are capable of antigen-positive platelet destruction in the NOD/SCID mouse model of alloimmune thrombocytopenia.
description
2011 nî lūn-bûn
@nan
2011 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@ast
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@en
type
label
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@ast
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@en
prefLabel
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@ast
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@en
P2093
P2860
P1433
P1476
Low-avidity anti-HPA-1a alloan ...... f alloimmune thrombocytopenia.
@en
P2093
Annika Krautwurst
Gregor Bein
Hans C Siebert
Monika Roderfeld
Sebastian Kubiak
Tamam Bakchoul
Ulrich J Sachs
P2860
P304
P356
10.1111/J.1537-2995.2011.03171.X
P577
2011-05-12T00:00:00Z