PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function. - Wikidata - wikimedia - TriplyDB

PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.

PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.

http://www.wikidata.org/entity/Q33395759

about

Cellular Response upon Stress: p57 Contribution to the Final Outcome An emerging role for prdm family genes in dorsoventral patterning of the vertebrate nervous system Meta-analysis identifies a MECOM gene as a novel predisposing factor of osteoporotic fracture Identification of Prdm genes in human corneal endothelium.Tissue-specific upregulation of MDS/EVI gene transcripts in the intestine by thyroid hormone during Xenopus metamorphosis.Global Identification of EVI1 Target Genes in Acute Myeloid Leukemia.Two decades of leukemia oncoprotein epistasis: the MLL1 paradigm for epigenetic deregulation in leukemia.Deletion of Mecom in mouse results in early-onset spinal deformity and osteopenia.Mice carrying a hypomorphic Evi1 allele are embryonic viable but exhibit severe congenital heart defects Evi1 is essential for hematopoietic stem cell self-renewal, and its expression marks hematopoietic cells with long-term multilineage repopulating activity Single-cell transcriptomic reconstruction reveals cell cycle and multi-lineage differentiation defects in Bcl11a-deficient hematopoietic stem cells.Comparative long-term effects of interferon α and hydroxyurea on human hematopoietic progenitor cells.PRDM14 promotes RAG-dependent Notch1 driver mutations in mouse T-ALL.Delineating the mixed lineage leukemia gene expression network in hematopoietic stem cells.An MLL-dependent network sustains hematopoiesis.EVI1 Interferes with Myeloid Maturation via Transcriptional Repression of Cebpa, via Binding to Two Far Downstream Regulatory Elements.BRPF1 is essential for development of fetal hematopoietic stem cells Essential role of PR-domain protein MDS1-EVI1 in MLL-AF9 leukemia.Genomic and proteomic analyses of Prdm5 reveal interactions with insulator binding proteins in embryonic stem cells.Cadherins Associate with Distinct Stem Cell-Related Transcription Factors to Coordinate the Maintenance of Stemness in Triple-Negative Breast Cancer.PRDM proteins: important players in differentiation and disease.Ecotropic viral integration site 1, stem cell self-renewal and leukemogenesis.Less is more: unveiling the functional core of hematopoietic stem cells through knockout mice.Imprinted genes in myeloid lineage commitment in normal and malignant hematopoiesis.Functional features of EVI1 and EVI1Δ324 isoforms of MECOM gene in genome-wide transcription regulation and oncogenicity.Recent advances in elucidating the genetic mechanisms of nephrogenesis using zebrafish.Activation of Evi1 inhibits cell cycle progression and differentiation of hematopoietic progenitor cells.Critical role of Jak2 in the maintenance and function of adult hematopoietic stem cells.Zebrafish nephrogenesis is regulated by interactions between retinoic acid, mecom, and Notch signaling.Nfix is a novel regulator of murine hematopoietic stem and progenitor cell survival.The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina.Genetic and Epigenetic Control of CDKN1C Expression: Importance in Cell Commitment and Differentiation, Tissue Homeostasis and Human Diseases.EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription

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P2860

PR-domain-containing Mds1-Evi1 is critical for long-term hematopoietic stem cell function.

http://www.wikidata.org/entity/Q33395759

description

2011 nî lūn-bûn

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2011 թուականի Յունիսին հրատարակուած գիտական յօդուած

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2011 թվականի հունիսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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type

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PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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PR-domain-containing Mds1-Evi1 ...... atopoietic stem cell function.

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Archibald S Perkins

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Charles A Wuertzer

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Fernando Camargo

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Gouri Chatterjee

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Kimberly Lezon-Geyda

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Lucie Coillard

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Sandra Stehling-Sun

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Yi Zhang

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P2860

Oligomerization of Evi-1 regulated by the PR domain contributes to recruitment of corepressor CtBP

The retinoblastoma protein binds to RIZ, a zinc-finger protein that shares an epitope with the adenovirus E1A protein

Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family

Identification and characterization of a novel repressor of beta-interferon gene expression

Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression

Structure and catalytic mechanism of a SET domain protein methyltransferase

EVI1 is expressed in megakaryocyte cell lineage and enforced expression of EVI1 in UT-7/GM cells induces megakaryocyte differentiation

Repression of bone morphogenetic protein and activin-inducible transcription by Evi-1

Blimp-1, a novel zinc finger-containing protein that can drive the maturation of B lymphocytes into immunoglobulin-secreting cells

The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3

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3853-3861

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10.1182/BLOOD-2011-02-334680

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