Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study.
about
Present Advances and Future Perspectives of Molecular Targeted Therapy for OsteosarcomaReceptor tyrosine kinases: Characterisation, mechanism of action and therapeutic interests for bone cancersEarly phase clinical trials of anticancer agents in children and adolescents - an ITCC perspective.Off-label use of targeted therapies in osteosarcomas: data from the French registry OUTC'S (Observatoire de l'Utilisation des Thérapies Ciblées dans les Sarcomes).Tolerability and pharmacokinetic profile of a sunitinib powder formulation in pediatric patients with refractory solid tumors: a Children's Oncology Group studyCardiovascular disease in adult survivors of childhood cancer.Combining targeted agents with modern radiotherapy in soft tissue sarcomas.Growth plate abnormalities in pediatric cancer patients undergoing phase 1 anti-angiogenic therapy: a report from the Children's Oncology Group Phase I Consortium.Challenges of clinical trial design for targeted agents against pediatric leukemias.Circulating endothelial progenitor cells in castration resistant prostate cancer: a randomized, controlled, biomarker study.Managing chemotherapy-related cardiotoxicity in survivors of childhood cancers.Clinical development of VEGF signaling pathway inhibitors in childhood solid tumors.Molecular profiling of childhood cancer: Biomarkers and novel therapiesOntogeny and sorafenib metabolism.The Tyrosine Kinase Inhibitor Sunitinib Affects Ovulation but Not Ovarian Reserve in Mouse: A Preclinical StudyNeurotoxicity of biologically targeted agents in pediatric cancer trialsThe combination of novel targeted molecular agents and radiation in the treatment of pediatric gliomas.Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas.A review of targeted therapies evaluated by the pediatric preclinical testing program for osteosarcoma.Phase I pharmacokinetic and pharmacodynamic study of pazopanib in children with soft tissue sarcoma and other refractory solid tumors: a children's oncology group phase I consortium report.Phase II evaluation of sunitinib in the treatment of recurrent or refractory high-grade glioma or ependymoma in children: a children's Oncology Group Study ACNS1021.Optimal management of Ewing sarcoma family of tumors: recent developments in systemic therapy.Drugs targeting the bone microenvironment: new therapeutic tools in Ewing's sarcoma?The potential of sunitinib as a therapy in ovarian cancer.Targeted therapies for bone sarcomas.Targeted therapy in pediatric low-grade glioma.The angiogenic asset of soft tissue sarcomas: a new tool to discover new therapeutic targets.Targeted approaches to childhood cancer: progress in drug discovery and development.Pericytes in sarcomas of bone.Physiological, Tumor, and Metastatic Niches: Opportunities and Challenges for Targeting the Tumor Microenvironment.Benefit, Risk, and Outcomes in Drug Development: A Systematic Review of Sunitinib.Drugs in early clinical development for the treatment of osteosarcoma.A comparison of safety and efficacy of cytotoxic versus molecularly targeted drugs in pediatric phase I solid tumor oncology trials.Conventional chemotherapy and perspectives for molecular-based oncological treatment in pediatric hemispheric low-grade gliomas.Lessons learned from adult clinical experience to inform evaluations of VEGF pathway inhibitors in children with cancer.Anti-angiogenesis target therapy for advanced osteosarcoma (Review).MAPK/ERK Signaling in Osteosarcomas, Ewing Sarcomas and Chondrosarcomas: Therapeutic Implications and Future Directions.Bone sarcomas: from biology to targeted therapies.Targeting FLT3 Signaling in Childhood Acute Myeloid Leukemia.Biomechanical regulation of drug sensitivity in an engineered model of human tumor.
P2860
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P2860
Phase I and pharmacokinetic study of sunitinib in pediatric patients with refractory solid tumors: a children's oncology group study.
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@ast
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@en
type
label
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@ast
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@en
prefLabel
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@ast
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@en
P2093
P2860
P1476
Phase I and pharmacokinetic st ...... ildren's oncology group study.
@en
P2093
Ashish M Ingle
Charlotte H Ahern
Holcombe E Grier
Joel M Reid
Julia Glade-Bender
Peter C Adamson
Steven G Dubois
Suzanne Shusterman
P2860
P304
P356
10.1158/1078-0432.CCR-11-0237
P407
P577
2011-06-20T00:00:00Z