Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions - Wikidata - wikimedia - TriplyDB

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

http://www.wikidata.org/entity/Q33396938

about

The role of sphingosine-1-phosphate transporter Spns2 in immune system function Sphingosine 1-phosphate lyase, a key regulator of sphingosine 1-phosphate signaling and function The SphKs/S1P/S1PR1 axis in immunity and cancer: more ore to be mined Genetic deletion of Mst1 alters T cell function and protects against autoimmunity Detection of host-derived sphingosine by Pseudomonas aeruginosa is important for survival in the murine lung Congenital hydrocephalus in genetically engineered mice Sphingosine-1-Phosphate Metabolism and Its Role in the Development of Inflammatory Bowel Disease S1P3-mediated cardiac fibrosis in sphingosine kinase 1 transgenic mice involves reactive oxygen species.Down-regulation of S1P1 receptor surface expression by protein kinase C inhibition.Sphingosine 1-phosphate lyase deficiency disrupts lipid homeostasis in liver S1pping fire: Sphingosine-1-phosphate signaling as an emerging target in inflammatory bowel disease and colitis-associated cancer Vascular and Immunobiology of the Circulatory Sphingosine 1-Phosphate Gradient.Mechanisms of fingolimod's efficacy and adverse effects in multiple sclerosis.S1P metabolism in cancer and other pathological conditions.Dual functions of the trans-2-enoyl-CoA reductase TER in the sphingosine 1-phosphate metabolic pathway and in fatty acid elongation.Sphingosine-1-phosphate enhances satellite cell activation in dystrophic muscles through a S1PR2/STAT3 signaling pathway.Calcitonin controls bone formation by inhibiting the release of sphingosine 1-phosphate from osteoclasts.An update on sphingosine-1-phosphate and other sphingolipid mediators.Sphingosine-1-phosphate and immune regulation: trafficking and beyond Sphingosine-1-phosphate lyase deficiency produces a pro-inflammatory response while impairing neutrophil trafficking.Distinct roles for hematopoietic and extra-hematopoietic sphingosine kinase-1 in inflammatory bowel disease.Hematopoietic sphingosine 1-phosphate lyase deficiency decreases atherosclerotic lesion development in LDL-receptor deficient mice S1P lyase: a novel therapeutic target for ischemia-reperfusion injury of the heart.S1P lyase regulates DNA damage responses through a novel sphingolipid feedback mechanism.S1P is associated with protection in human and experimental cerebral malaria Sphingosine-1-phosphate lyase downregulation promotes colon carcinogenesis through STAT3-activated microRNAs.Tumor-suppressive sphingosine-1-phosphate receptor-2 counteracting tumor-promoting sphingosine-1-phosphate receptor-1 and sphingosine kinase 1 - Jekyll Hidden behind Hyde Emerging biology of sphingosine-1-phosphate: its role in pathogenesis and therapy.An emerging role for the lipid mediator sphingosine-1-phosphate in mast cell effector function and allergic disease.High-throughput screening of mouse gene knockouts identifies established and novel skeletal phenotypes.The outs and the ins of sphingosine-1-phosphate in immunity Sphingosine-1-phosphate lyase expression in embryonic and adult murine tissues Spinster 2, a sphingosine-1-phosphate transporter, plays a critical role in inflammatory and autoimmune diseases.Shaping the landscape: metabolic regulation of S1P gradients.Truth and consequences of sphingosine-1-phosphate lyase.Immunohistochemical analysis of sphingosine phosphate lyase expression during murine development.Sphingosine-1-phosphate in inflammatory bowel disease and colitis-associated colon cancer: the fat's in the fire Sphingosine-1-phosphate, FTY720, and sphingosine-1-phosphate receptors in the pathobiology of acute lung injury.Aging-related elevation of sphingoid bases shortens yeast chronological life span by compromising mitochondrial function Sphingosine-1-phosphate can promote mast cell hyper-reactivity through regulation of contactin-4 expression.

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Incomplete inhibition of sphingosine 1-phosphate lyase modulates immune system function yet prevents early lethality and non-lymphoid lesions

http://www.wikidata.org/entity/Q33396938

description

2009 nî lūn-bûn

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2009 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2009 թվականի հունվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Incomplete inhibition of sphin ...... ality and non-lymphoid lesions

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Incomplete inhibition of sphin ...... ality and non-lymphoid lesions

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type

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Incomplete inhibition of sphin ...... ality and non-lymphoid lesions

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Incomplete inhibition of sphin ...... ality and non-lymphoid lesions

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Incomplete inhibition of sphin ...... ality and non-lymphoid lesions

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Incomplete inhibition of sphin ...... ality and non-lymphoid lesions

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Gwenn M Hansen

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Jill Hazlewood

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Jonathan Swaffield

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Michael S Donoviel

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Robert Read

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Stephen J Anderson

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Tamas Oravecz

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Weimei Sun

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P2860

Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis

Sphingosine 1-phosphate as a regulator of osteoclast differentiation and osteoclast-osteoblast coupling

S1P1 receptor signaling overrides retention mediated by G alpha i-coupled receptors to promote T cell egress

Sphingosine-1-phosphate lyase potentiates apoptosis via p53- and p38-dependent pathways and is down-regulated in colon cancer

The BST1 gene of Saccharomyces cerevisiae is the sphingosine-1-phosphate lyase.

Sphingosine kinases, sphingosine 1-phosphate, apoptosis and diseases

Subcellular localization and membrane topology of sphingosine-1-phosphate lyase in rat liver

Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention

PDGF signaling specificity is mediated through multiple immediate early genes

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

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