An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.
about
The HIV-1 integrase α4-helix involved in LTR-DNA recognition is also a highly antigenic peptide elementPiecing together the structure of retroviral integrase, an important target in AIDS therapySpecificity of LTR DNA recognition by a peptide mimicking the HIV-1 integrase {alpha}4 helix.Characterization of the HIV-1 integrase chromatin- and LEDGF/p75-binding abilities by mutagenic analysis within the catalytic core domain of integrase.Insight into the inhibitory mechanism and binding mode between D77 and HIV-1 integrase by molecular modeling methods.
P2860
An unusual helix turn helix motif in the catalytic core of HIV-1 integrase binds viral DNA and LEDGF.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@ast
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@en
type
label
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@ast
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@en
prefLabel
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@ast
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@en
P2093
P2860
P1433
P1476
An unusual helix turn helix mo ...... ase binds viral DNA and LEDGF.
@en
P2093
Brigitte René
Hayate Merad
Horea Porumb
Loussiné Zargarian
Olivier Mauffret
Richard G Maroun
Serge Fermandjian
Zeina Hobaika
P2860
P356
10.1371/JOURNAL.PONE.0004081
P407
P577
2009-01-01T00:00:00Z