Dynamic antibody-binding properties in the pathogenesis of HIT.
about
Atomic description of the immune complex involved in heparin-induced thrombocytopeniaAntigen and substrate withdrawal in the management of autoimmune thrombotic disorders.Novel diagnostic assays for heparin-induced thrombocytopeniaEmphasis on the Role of PF4 in the Incidence, Pathophysiology and Treatment of Heparin Induced Thrombocytopenia.Complex formation with nucleic acids and aptamers alters the antigenic properties of platelet factor 4.Distinct specificity and single-molecule kinetics characterize the interaction of pathogenic and non-pathogenic antibodies against platelet factor 4-heparin complexes with platelet factor 4.Correlation of ELISA optical density with clinical diagnosis of heparin-induced thrombocytopenia: a retrospective study of 104 patients with positive anti-PF4/heparin ELISA.Platelet factor 4/heparin-particle gel immunoassay (PaGIA) is a weak method for heparin-induced thrombocytopenia (HIT) evaluation of post cardio-pulmonary bypass surgery patients.Advances in the pathophysiology and treatment of heparin-induced thrombocytopenia.Heparin enhances uptake of platelet factor 4/heparin complexes by monocytes and macrophagesPlatelet transactivation by monocytes promotes thrombosis in heparin-induced thrombocytopenia.Atomic features of an autoantigen in heparin-induced thrombocytopenia (HIT).Efficacy and Safety of Fondaparinux in Patients With Suspected Heparin-Induced Thrombocytopenia.A high-value cost conscious approach to minimize heparin induced thrombocytopenia antibody (HITAb) testing using the 4T score.Single-molecule force spectroscopy applied to heparin-induced thrombocytopenia.New platelet functional method for identification of pathogenic antibodies in HIT patients.Anti-platelet factor 4/polyanion antibodies mediate a new mechanism of autoimmunity.Effect of pH and ionic strength on the binding strength of anti-PF4/polyanion antibodies.The diversity of the immune response to the A2 domain of human factor VIIIPlatelet Factor 4 Inhibits and Enhances HIV-1 Infection in a Concentration-Dependent Manner by Modulating Viral AttachmentAutoimmune heparin-induced thrombocytopenia.Development of a high-yield expression and purification system for platelet factor 4.5B9, a monoclonal antiplatelet factor 4/heparin IgG with a human Fc fragment that mimics heparin-induced thrombocytopenia antibodies.The Role of Single-Molecule Force Spectroscopy in Unraveling Typical and Autoimmune Heparin-induced Thrombocytopenia.Neutrophil accumulation and NET release contribute to thrombosis in HIT
P2860
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P2860
Dynamic antibody-binding properties in the pathogenesis of HIT.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Dynamic antibody-binding properties in the pathogenesis of HIT.
@ast
Dynamic antibody-binding properties in the pathogenesis of HIT.
@en
type
label
Dynamic antibody-binding properties in the pathogenesis of HIT.
@ast
Dynamic antibody-binding properties in the pathogenesis of HIT.
@en
prefLabel
Dynamic antibody-binding properties in the pathogenesis of HIT.
@ast
Dynamic antibody-binding properties in the pathogenesis of HIT.
@en
P2093
P2860
P1433
P1476
Dynamic antibody-binding properties in the pathogenesis of HIT.
@en
P2093
Adam Cuker
Bruce S Sachais
Douglas B Cines
Gowthami M Arepally
Jillian L Hinds
John W Weisel
Lubica Rauova
Mortimer Poncz
Serge V Yarovoi
P2860
P304
P356
10.1182/BLOOD-2012-01-407262
P407
P577
2012-05-10T00:00:00Z