A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine.
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Novel approaches to target HER2-positive breast cancer: trastuzumab emtansineRole of trastuzumab emtansine in the treatment of HER2-positive breast cancerSerum biomarkers for the detection of cardiac toxicity after chemotherapy and radiation therapy in breast cancer patientsImmunotherapy in gastric cancerProfiling and targeting HER2-positive breast cancer using trastuzumab emtansineThe development of immunoconjugates for targeted cancer therapyTrastuzumab emtansine for HER2-positive advanced breast cancer.Whether HER2-positive non-breast cancers are candidates for treatment with Ado-trastuzumab emtansine?Twenty years of anti-HER2 therapy-associated cardiotoxicityRecent advances in the development of anti-HER2 antibodies and antibody-drug conjugatesMechanisms of action of therapeutic antibodies for cancerAdo-trastuzumab emtansine (T-DM1): a novel antibody-drug conjugate for the treatment of HER2-positive metastatic breast cancer.Trastuzumab emtansine in the treatment of HER2-positive metastatic breast cancer in Japanese patientsAdo-trastuzumab emtansine-associated telangiectasias in metastatic breast cancer: a case series.Phase I and pharmacokinetic study of trastuzumab emtansine in Japanese patients with HER2-positive metastatic breast cancer.Dose-reduced trastuzumab emtansine: active and safe in acute hepatic dysfunctionA multicenter Phase II study evaluating the efficacy, safety and pharmacokinetics of trastuzumab emtansine in Japanese patients with heavily pretreated HER2-positive locally recurrent or metastatic breast cancer.Safety and Efficacy of Trastuzumab Emtansine in Advanced Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer: a Meta-analysis.Ethnic sensitivity assessment of the antibody-drug conjugate trastuzumab emtansine (T-DM1) in patients with HER2-positive locally advanced or metastatic breast cancer.Safety Evaluation of Trastuzumab Emtansine in Japanese Patients with HER2-Positive Advanced Breast Cancer.Emerging therapies for breast cancerAdo-Trastuzumab Emtansine in Metastatic HER2-Positive Breast Cancer.Population pharmacokinetics of trastuzumab emtansine (T-DM1), a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer: clinical implications of the effect of covariates.Therapeutic options for HER-2 positive breast cancer: Perspectives and future directionsCurrent status of anti-human epidermal growth factor receptor 2 therapies: predicting and overcoming herceptin resistanceAdo-trastuzumab emtansine (T-DM1) in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer: latest evidence and clinical potentialGene status in HER2 equivocal breast carcinomas: impact of distinct recommendations and contribution of a polymerase chain reaction-based method.HER2-positive advanced breast cancer: optimizing patient outcomes and opportunities for drug development.Relationship between HER2 expression and efficacy with first-line trastuzumab emtansine compared with trastuzumab plus docetaxel in TDM4450g: a randomized phase II study of patients with previously untreated HER2-positive metastatic breast cancer.Dual HER2 targeting impedes growth of HER2 gene-amplified uterine serous carcinoma xenograftsTreatment of HER2-positive breast cancer.Antibody Drug Conjugates: Nonclinical Safety Considerations.Targeting HER2 Positive Breast Cancer with Chemopreventive Agents.Splenic Enlargement and Bone Marrow Hyperplasia in Patients Receiving Trastuzumab-Emtansine for Metastatic Breast Cancer.A Pictet-Spengler ligation for protein chemical modificationTrastuzumab-DM1: a clinical update of the novel antibody-drug conjugate for HER2-overexpressing breast cancerClinical efficacy and safety of T-DM1 for patients with HER2-positive breast cancerβ-catenin-independent WNT signaling and Ki67 in contrast to the estrogen receptor status are prognostic and associated with poor prognosis in breast cancer liver metastasesPhase I/II study of the antibody-drug conjugate glembatumumab vedotin in patients with advanced melanoma.Anti-HER2 Therapy Beyond Second-Line for HER2-Positive Metastatic Breast Cancer: A Short Review and Recommendations for Several Clinical Scenarios from a Spanish Expert Panel.
P2860
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P2860
A phase II study of trastuzumab emtansine in patients with human epidermal growth factor receptor 2-positive metastatic breast cancer who were previously treated with trastuzumab, lapatinib, an anthracycline, a taxane, and capecitabine.
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年学术文章
@wuu
2012年学术文章
@zh-cn
2012年学术文章
@zh-hans
2012年学术文章
@zh-my
2012年学术文章
@zh-sg
2012年學術文章
@yue
name
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@ast
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@en
type
label
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@ast
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@en
prefLabel
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@ast
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@en
P2093
P356
P1476
A phase II study of trastuzuma ...... e, a taxane, and capecitabine.
@en
P2093
Denise Yardley
Ellie Guardino
Eric P Winer
Gladys Rodriguez
Hope S Rugo
Ian E Krop
Kathy D Miller
Lukas Amler
Maoxia Zheng
Michael Lu
P304
P356
10.1200/JCO.2011.40.5902
P407
P50
P577
2012-05-29T00:00:00Z