about
Novel roles of holocarboxylase synthetase in gene regulation and intermediary metabolismBiotinylation, a post-translational modification controlled by the rate of protein-protein association.Selectivity in post-translational biotin addition to five human carboxylases.Selective overexpression of human SIRT1 in adipose tissue enhances energy homeostasis and prevents the deterioration of insulin sensitivity with ageing in miceDistinct amino termini of two human HCS isoforms influence biotin acceptor substrate recognition.Initial characterization of histone H3 serine 10 O-acetylation.Repression of transposable elements by histone biotinylation.Epigenome manipulation as a pathway to new natural product scaffolds and their congeners.Biotinylation is a natural, albeit rare, modification of human histones.Holocarboxylase synthetase is a chromatin protein and interacts directly with histone H3 to mediate biotinylation of K9 and K18.Human holocarboxylase synthetase with a start site at methionine-58 is the predominant nuclear variant of this protein and has catalytic activity.The polypeptide Syn67 interacts physically with human holocarboxylase synthetase, but is not a target for biotinylationHolocarboxylase synthetase 1 physically interacts with histone h3 in Arabidopsis.The role of holocarboxylase synthetase in genome stability is mediated partly by epigenomic synergies between methylation and biotinylation events.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
Nonenzymatic biotinylation of histone H2A.
@ast
Nonenzymatic biotinylation of histone H2A.
@en
type
label
Nonenzymatic biotinylation of histone H2A.
@ast
Nonenzymatic biotinylation of histone H2A.
@en
prefLabel
Nonenzymatic biotinylation of histone H2A.
@ast
Nonenzymatic biotinylation of histone H2A.
@en
P2093
P2860
P356
P1433
P1476
Nonenzymatic biotinylation of histone H2A.
@en
P2093
David Schriemer
Laura Hohmann
Roy A Gravel
Shannon Healy
Tom D Heightman
P2860
P304
P356
10.1002/PRO.37
P577
2009-02-01T00:00:00Z