Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth.
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An informatic pipeline for managing high-throughput screening experiments and analyzing data from stereochemically diverse librariesAn aldol-based build/couple/pair strategy for the synthesis of medium- and large-sized rings: discovery of macrocyclic histone deacetylase inhibitors.Fragment-based domain shuffling approach for the synthesis of pyran-based macrocycles.1,3-allylic strain as a strategic diversification element for constructing libraries of substituted 2-arylpiperidines.Translating Nature's Library: The Bryostatins and Function-Oriented SynthesisSynthesis and profiling of a diverse collection of azetidine-based scaffolds for the development of CNS-focused lead-like libraries.Concise synthesis and biological assessment of (+)-neopeltolide and a 16-member stereoisomer library of 8,9-dehydroneopeltolide: identification of pharmacophoric elements.INTEGRATED APPROACHES TO THE CONFIGURATIONAL ASSIGNMENT OF MARINE NATURAL PRODUCTSHits, leads and drugs against malaria through diversity-oriented synthesis.Cyclin-dependent kinase inhibitor 3 (CDKN3) novel cell cycle computational network between human non-malignancy associated hepatitis/cirrhosis and hepatocellular carcinoma (HCC) transformation.Design, synthesis, and biological evaluation of simplified side chain hybrids of the potent actin binding polyketides rhizopodin and bistramide.Natural product analogues: towards a blueprint for analogue-focused synthesis.Practical asymmetric synthesis of β-hydroxy γ-amino acids via complimentary aldol reactions.Diversity-oriented synthesis of 13- to 18-membered macrolactams via ring-closing metathesis.Catalytic diastereoselective petasis reactionsLarge-scale synthesis of all stereoisomers of a 2,3-unsaturated C-glycoside scaffold.Total synthesis of bistramide A and its 36(Z) isomers: differential effect on cell division, differentiation, and apoptosis.Ascidian Toxins with Potential for Drug Development.
P2860
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P2860
Synthesis of a 35-member stereoisomer library of bistramide A: evaluation of effects on actin state, cell cycle and tumor cell growth.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@ast
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@en
type
label
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@ast
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@en
prefLabel
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@ast
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@en
P2093
P2860
P356
P1476
Synthesis of a 35-member stere ...... l cycle and tumor cell growth.
@en
P2093
Iwona E Wrona
James S Panek
Jason T Lowe
Julien Beignet
Tanya R Johnson
Thomas J Turbyville
P2860
P304
P356
10.1021/JO802269Q
P407
P577
2009-03-01T00:00:00Z