Immunological applications of single-domain llama recombinant antibodies isolated from a naïve library.
about
Recombinant antibody production evolves into multiple options aimed at yielding reagents suitable for application-specific needsA Single-Domain Llama Antibody Potently Inhibits the Enzymatic Activity of Botulinum Neurotoxin by Binding to the Non-Catalytic α-Exosite Binding RegionJoining the in vitro immunization of alpaca lymphocytes and phage display: rapid and cost effective pipeline for sdAb synthesisA V H H that neutralizes the zinc metalloproteinase activity of botulinum neurotoxin type AThe availability of a recombinant anti-SNAP antibody in VHH format amplifies the application flexibility of SNAP-tagged proteins.Diagnostic evaluation of a nanobody with picomolar affinity toward the protease RgpB from Porphyromonas gingivalis.Prolonged prophylactic protection from botulism with a single adenovirus treatment promoting serum expression of a VHH-based antitoxin protein.Methodologies for the isolation of alternative binders with improved clinical potentiality over conventional antibodies.Bacterial cytoplasm as an effective cell compartment for producing functional VHH-based affinity reagents and Camelidae IgG-like recombinant antibodiesDetection of cystatin C biomarker for clinical measurement of renal disease by developed ELISA diagnostic kitsConstruction of a synthetic phage-displayed Nanobody library with CDR3 regions randomized by trinucleotide cassettes for diagnostic applications.Selection of single domain antibodies from immune libraries displayed on the surface of E. coli cells with two β-domains of opposite topologies.Single-domain antibodies and their utility.Development of VHH antibodies against dengue virus type 2 NS1 and comparison with monoclonal antibodies for use in immunological diagnosis.Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells.Selection by phage display of nanobodies directed against hypoxia inducible factor-1α (HIF-1α).Characterization and applications of Nanobodies against human procalcitonin selected from a novel naïve Nanobody phage display library.Single domain antibodies for the knockdown of cytosolic and nuclear proteins.Nanobody(R)-based chromatin immunoprecipitation/micro-array analysis for genome-wide identification of transcription factor DNA binding sites.Antibody light chain variable domains and their biophysically improved versions for human immunotherapy.Biotechnological applications of recombinant single-domain antibody fragments.Development of proteome-wide binding reagents for research and diagnostics.Nanobodies as novel agents for disease diagnosis and therapy.Single-domain antibodies for biomedical applications.Novel antibody derivatives for proteome and high-content analysis.Molecular dynamics simulations and docking enable to explore the biophysical factors controlling the yields of engineered nanobodies.Escherichia coli surface display for the selection of nanobodies.Nanobodies and their potential applications.Engineered cross-reacting nanobodies simplify comparative oncology between humans and dogs.Camelid Single-Domain Antibodies: Historical Perspective and Future Outlook.Nanobodies: Chemical Functionalization Strategies and Intracellular Applications.Isolation of anti-extra-cellular vesicle single-domain antibodies by direct panning on vesicle-enriched fractions.Quantification of Circulating Cancer Biomarkers via Sensitive Topographic Measurements on Single Binder Nanoarrays.
P2860
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P2860
Immunological applications of single-domain llama recombinant antibodies isolated from a naïve library.
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Immunological applications of ...... isolated from a naïve library.
@ast
Immunological applications of ...... isolated from a naïve library.
@en
type
label
Immunological applications of ...... isolated from a naïve library.
@ast
Immunological applications of ...... isolated from a naïve library.
@en
prefLabel
Immunological applications of ...... isolated from a naïve library.
@ast
Immunological applications of ...... isolated from a naïve library.
@en
P2093
P2860
P50
P356
P1476
Immunological applications of ...... isolated from a naïve library.
@en
P2093
Ana Monegal
Ario de Marco
Giuseppe Ossolengo
Marisa Aliprandi
Paola Capasso
P2860
P304
P356
10.1093/PROTEIN/GZP002
P577
2009-02-04T00:00:00Z