A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
about
Cardiovascular complications in atypical haemolytic uraemic syndrome.A novel atypical hemolytic uremic syndrome-associated hybrid CFHR1/CFH gene encoding a fusion protein that antagonizes factor H-dependent complement regulation.The major autoantibody epitope on factor H in atypical hemolytic uremic syndrome is structurally different from its homologous site in factor H-related protein 1, supporting a novel model for induction of autoimmunity in this disease.A De Novo Deletion in the Regulators of Complement Activation Cluster Producing a Hybrid Complement Factor H/Complement Factor H-Related 3 Gene in Atypical Hemolytic Uremic Syndrome.Human factor H-related protein 2 (CFHR2) regulates complement activation.Kidney Disease Caused by Dysregulation of the Complement Alternative Pathway: An Etiologic Approach.Complement Factor H-Related 5-Hybrid Proteins Anchor Properdin and Activate Complement at Self-Surfaces.All Things Complement.Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome.FHR-1 Binds to C-Reactive Protein and Enhances Rather than Inhibits Complement Activation.Recurrent structural variation, clustered sites of selection, and disease risk for the complement factor H (CFH) gene family.Hemolytic uremic syndrome
P2860
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P2860
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
description
2013 nî lūn-bûn
@nan
2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@ast
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@en
type
label
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@ast
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@en
prefLabel
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@ast
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@en
P2093
P2860
P1433
P1476
A novel hybrid CFHR1/CFH gene causes atypical hemolytic uremic syndrome
@en
P2093
Carla M Nester
Nicole C Meyer
Richard J H Smith
Stephen J Eyler
Yuzhou Zhang
P2860
P2888
P304
P356
10.1007/S00467-013-2560-2
P577
2013-07-24T00:00:00Z
P6179
1002874292