about
Intrinsically unstructured domain 3 of hepatitis C Virus NS5A forms a "fuzzy complex" with VAPB-MSP domain which carries ALS-causing mutationsInsights into protein aggregation by NMR characterization of insoluble SH3 mutants solubilized in salt-free waterStructural, stability, dynamic and binding properties of the ALS-causing T46I mutant of the hVAPB MSP domain as revealed by NMR and MD simulationsNMR and MD Studies Reveal That the Isolated Dengue NS3 Protease Is an Intrinsically Disordered Chymotrypsin Fold Which Absolutely Requests NS2B for Correct Folding and Functional DynamicsDenatured mammalian protein mixtures exhibit unusually high solubility in nucleic acid-free pure water.RRM domain of ALS/FTD-causing FUS characteristic of irreversible unfolding spontaneously self-assembles into amyloid fibrils.Selective and specific ion binding on proteins at physiologically-relevant concentrations.Resolving the paradox for protein aggregation diseases: NMR structure and dynamics of the membrane-embedded P56S-MSP causing ALS imply a common mechanism for aggregation-prone proteins to attack membranesTDP-43 N terminus encodes a novel ubiquitin-like fold and its unfolded form in equilibrium that can be shifted by binding to ssDNAALS-Causing Mutations Significantly Perturb the Self-Assembly and Interaction with Nucleic Acid of the Intrinsically Disordered Prion-Like Domain of TDP-43.Why do proteins aggregate? "Intrinsically insoluble proteins" and "dark mediators" revealed by studies on "insoluble proteins" solubilized in pure water.Molecular simulations of protein disorder.Environment-transformable sequence-structure relationship: a general mechanism for proteotoxicity.
P2860
Q21560973-06F71D3F-E42E-4A08-9239-A64DD0998E3DQ28471978-79E937BA-A6ED-47F1-98F7-3A1A8668285DQ28477745-696246C0-9FE5-4FB7-BDF8-162D4AAEEBA3Q28547136-3FB6CE24-98AD-4437-B4DD-9DD8C86E98DFQ30870411-6A3628A1-8901-4B9A-8850-CAEE293F7D22Q33683022-C674E4A6-42DE-4E9C-82E1-BB95AAA349A1Q34015779-1EFA9072-ABFD-4417-8328-2E32EC46A598Q34211441-E5F3CC8D-53CF-47A2-BC56-B17C130AE4DAQ34831850-A6E5E850-67F0-4D1B-9338-2DAEAC679D6FQ35886826-30EBF255-ECF7-4744-99F5-9604F05C7EDBQ37406805-30C3CE21-C2F4-42BA-912A-A1C85DE9D766Q37746989-7630711C-B5A3-4505-85C5-EF06EF475828Q47330876-D4CFD9DA-1530-48AB-A82D-E662D6803388
P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Insight into "insoluble proteins" with pure water.
@ast
Insight into "insoluble proteins" with pure water.
@en
type
label
Insight into "insoluble proteins" with pure water.
@ast
Insight into "insoluble proteins" with pure water.
@en
prefLabel
Insight into "insoluble proteins" with pure water.
@ast
Insight into "insoluble proteins" with pure water.
@en
P2860
P1433
P1476
Insight into "insoluble proteins" with pure water.
@en
P2860
P304
P356
10.1016/J.FEBSLET.2009.02.022
P407
P577
2009-02-20T00:00:00Z