Three-dimensional structure of AAA ATPase Vps4: advancing structural insights into the mechanisms of endosomal sorting and enveloped virus budding.
about
Interactions of the human LIP5 regulatory protein with endosomal sorting complexes required for transportThe ESCRT complexesRegulation of Vps4 during MVB sorting and cytokinesisMembrane budding and scission by the ESCRT machinery: it's all in the neckAssembly and disassembly of the ESCRT-III membrane scission complexThe ESCRT machinery: from the plasma membrane to endosomes and back againAsymmetric ring structure of Vps4 required for ESCRT-III disassembly.Structural Role of the Vps4-Vta1 Interface in ESCRT-III RecyclingThe Oligomeric State of the Active Vps4 AAA ATPaseVfa1 Binds to the N-terminal Microtubule-interacting and Trafficking (MIT) Domain of Vps4 and Stimulates Its ATPase ActivityCrenarchaeal CdvA forms double-helical filaments containing DNA and interacts with ESCRT-III-like CdvBCoordinated binding of Vps4 to ESCRT-III drives membrane neck constriction during MVB vesicle formationAssembly of the AAA ATPase Vps4 on ESCRT-III.Coordination of substrate binding and ATP hydrolysis in Vps4-mediated ESCRT-III disassembly.Activation of human VPS4A by ESCRT-III proteins reveals ability of substrates to relieve enzyme autoinhibition.Vps4 disassembles an ESCRT-III filament by global unfolding and processive translocation.Binding of Substrates to the Central Pore of the Vps4 ATPase Is Autoinhibited by the Microtubule Interacting and Trafficking (MIT) Domain and Activated by MIT Interacting Motifs (MIMs).Conformational Changes in the Endosomal Sorting Complex Required for the Transport III Subunit Ist1 Lead to Distinct Modes of ATPase Vps4 RegulationThe linker region plays a regulatory role in assembly and activity of the Vps4 AAA ATPase.Reverse-topology membrane scission by the ESCRT proteins.Structure and function of the membrane deformation AAA ATPase Vps4.Dynamics of ESCRT proteins.Meiotic Clade AAA ATPases: Protein Polymer Disassembly Machines.Cryo-EM structures of the ATP-bound Vps4E233Q hexamer and its complex with Vta1 at near-atomic resolution.Identification and Characterization of BmVta1, a Bombyx mori (Lepidoptera: Bombycidae) Homologue for Vta1 That is Up-Regulated in Development.Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase.Recruitment dynamics of ESCRT-III and Vps4 to endosomes and implications for reverse membrane budding.Physical, Functional and Genetic Interactions between the BEACH Domain Protein SPIRRIG and LIP5 and SKD1 and Its Role in Endosomal Trafficking to the Vacuole in Arabidopsis.Inhibition of HBV replication by VPS4B and its dominant negative mutant VPS4B-K180Q in vivo.
P2860
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P2860
Three-dimensional structure of AAA ATPase Vps4: advancing structural insights into the mechanisms of endosomal sorting and enveloped virus budding.
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Three-dimensional structure of ...... g and enveloped virus budding.
@ast
Three-dimensional structure of ...... g and enveloped virus budding.
@en
type
label
Three-dimensional structure of ...... g and enveloped virus budding.
@ast
Three-dimensional structure of ...... g and enveloped virus budding.
@en
prefLabel
Three-dimensional structure of ...... g and enveloped virus budding.
@ast
Three-dimensional structure of ...... g and enveloped virus budding.
@en
P2093
P1433
P1476
Three-dimensional structure of ...... g and enveloped virus budding.
@en
P2093
Alan Leslie Munn
Parimala Rao Vajjhala
Rosalba Rothnagel
P304
P356
10.1016/J.STR.2008.12.020
P577
2009-03-01T00:00:00Z