Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.

Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.

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An Ultra-specific Avian Antibody to Phosphorylated Tau Protein Reveals a Unique Mechanism for Phosphoepitope Recognition Structural and Pharmacological Characterization of Novel Potent and Selective Monoclonal Antibody Antagonists of Glucose-dependent Insulinotropic Polypeptide Receptor The breadth of cross sub-type neutralisation activity of a single domain antibody to influenza hemagglutinin can be increased by antibody valency.Cross-Neutralising Nanobodies Bind to a Conserved Pocket in the Hemagglutinin Stem Region Identified Using Yeast Display and Deep Mutational Scanning.MF59 adjuvant enhances diversity and affinity of antibody-mediated immune response to pandemic influenza vaccines.CDR-restricted engineering of native human scFvs creates highly stable and soluble bifunctional antibodies for subcutaneous delivery.An efficient method for variable region assembly in the construction of scFv phage display libraries using independent strand amplification.Antibody affinity maturation using yeast display with detergent-solubilized membrane proteins as antigen sources Frontier of therapeutic antibody discovery: The challenges and how to face them.Improving the pharmacokinetic properties of biologics by fusion to an anti-HSA shark VNAR domain Augmented Binary Substitution: Single-pass CDR germ-lining and stabilization of therapeutic antibodies.Selection of Recombinant Human Antibodies.Antibody humanization methods - a review and update.Cellular mechanisms and consequences of glycation in atherosclerosis and obesity.Glycation & the RAGE axis: targeting signal transduction through DIAPH1.Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods.Imaging receptor for advanced glycation end product expression in mouse model of hind limb ischemia.Pharmacokinetics and lung distribution of a humanized anti-RAGE antibody in wild-type and RAGE-/- mice.In Vitro Maturation of a Humanized Shark VNAR Domain to Improve Its Biophysical Properties to Facilitate Clinical Development.Phage Display: A Powerful Technology for the Generation of High-Specificity Affinity Reagents from Alternative Immune Sources.RAGE-specific single chain Fv for PET imaging of pancreatic cancer.Antibody Phage Display

P2860

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P2860

Affinity maturation of a humanized rat antibody for anti-RAGE therapy: comprehensive mutagenesis reveals a high level of mutational plasticity both inside and outside the complementarity-determining regions.

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http://www.wikidata.org/entity/Q33418152

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