about
'The clocks that time us'--circadian rhythms in neurodegenerative disordersHuntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s diseaseEarly changes in the hypothalamic region in prodromal Huntington disease revealed by MRI analysis.The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling.Formation of polyglutamine inclusions in a wide range of non-CNS tissues in the HdhQ150 knock-in mouse model of Huntington's disease.Full-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expressionReducing Igf-1r levels leads to paradoxical and sexually dimorphic effects in HD mice.Reduced body mass index in essential tremor: a study of 382 cases and 392 matched controlsIs Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?Loss of the thyroid hormone-binding protein Crym renders striatal neurons more vulnerable to mutant huntingtin in Huntington's disease.Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease.Loss of huntingtin-associated protein 1 impairs insulin secretion from pancreatic β-cells.A 24-Hour Study of the Hypothalamo-Pituitary Axes in Huntington's Disease.Using Actiwatch to monitor circadian rhythm disturbance in Huntington' disease: A cautionary note.Characterization of Behavioral, Neuropathological, Brain Metabolic and Key Molecular Changes in zQ175 Knock-In Mouse Model of Huntington's DiseaseMetabolic and behavioral effects of mutant huntingtin deletion in Sim1 neurons in the BACHD mouse model of Huntington's disease.Insulin-Like Growth Factor-1 but Not Insulin Predicts Cognitive Decline in Huntington's Disease.Are BDNF and glucocorticoid activities calibrated?Epigallocatechin-3-gallate: a useful, effective and safe clinical approach for targeted prevention and individualised treatment of neurological diseases?Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice.A network model of genomic hormone interactions underlying dementia and its translational validation through serendipitous off-target effectIntrajugular vein delivery of AAV9-RNAi prevents neuropathological changes and weight loss in Huntington's disease mice.Androgen function in the pathophysiology and treatment of male Huntington's disease patients.Hypothalamic alterations in Huntington's disease patients: comparison with genetic rodent models.Regulation of L-type Ca2+ Channel Activity and Insulin Secretion by Huntingtin-associated Protein 1.Altered expression of 3-betahydroxysterol delta-24-reductase/selective Alzheimer's disease indicator-1 gene in Huntington's disease models.Activation of IGF-1 and insulin signaling pathways ameliorate mitochondrial function and energy metabolism in Huntington's Disease human lymphoblasts.Corticosterone dysregulation exacerbates disease progression in the R6/2 transgenic mouse model of Huntington's disease.Mutant huntingtin fragment selectively suppresses Brn-2 POU domain transcription factor to mediate hypothalamic cell dysfunctionGrowth hormone and ghrelin secretion are associated with clinical severity in Huntington's disease.The relationship between cortisol and verbal memory in the early stages of Huntington's disease.Therapeutic Effects of Anthocyanins and Environmental Enrichment in R6/1 Huntington's Disease Mice.Hypothalamic-pituitary-adrenal axis functioning in Huntington's disease and its association with depressive symptoms and suicidality.Deficits in spermatogenesis but not neurogenesis are alleviated by chronic testosterone therapy in R6/1 Huntington's disease mice.Paraventricular nucleus neuropeptide expression in Huntington's disease patients.Huntington's Disease and Diabetes: Chronological Sequence of its Association.Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.A Critical Evaluation of Wet Biomarkers for Huntington's Disease: Current Status and Ways Forward.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Neuroendocrine disturbances in Huntington's disease
@ast
Neuroendocrine disturbances in Huntington's disease
@en
type
label
Neuroendocrine disturbances in Huntington's disease
@ast
Neuroendocrine disturbances in Huntington's disease
@en
prefLabel
Neuroendocrine disturbances in Huntington's disease
@ast
Neuroendocrine disturbances in Huntington's disease
@en
P2093
P2860
P50
P1433
P1476
Neuroendocrine disturbances in Huntington's disease
@en
P2093
Emmanuel Broussolle
Françoise Morin
Nadine Saleh
Patrick Maison
Pierre Krystkowiak
Stéphane Moutereau
P2860
P356
10.1371/JOURNAL.PONE.0004962
P407
P577
2009-03-25T00:00:00Z