The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1.
about
Epigenetic features of human mesenchymal stem cells determine their permissiveness for induction of relevant transcriptional changes by SYT-SSX1.Cytosolic SYT/SS18 isoforms are actin-associated proteins that function in matrix-specific adhesion.Genome-wide recruitment to Polycomb-modified chromatin and activity regulation of the synovial sarcoma oncogene SYT-SSX2.Truncated SSX protein suppresses synovial sarcoma cell proliferation by inhibiting the localization of SS18-SSX fusion protein.Molecular marks for epigenetic identification of developmental and cancer stem cellsEpigenetic and epigenomic mechanisms shape sarcoma and other mesenchymal tumor pathogenesis.Ectopic expression of cancer/testis antigen SSX2 induces DNA damage and promotes genomic instability.SSX2 is a novel DNA-binding protein that antagonizes polycomb group body formation and gene repression.Epigenetic and genetic changes in soft tissue sarcomas: a review.Targeting the Wnt pathway in synovial sarcoma models.Subnuclear distribution of SSX regulates its function.Reprogramming of mesenchymal stem cells by the synovial sarcoma-associated oncogene SYT-SSX2.Downstream and intermediate interactions of synovial sarcoma-associated fusion oncoproteins and their implication for targeted therapy.Soft Tissue Sarcoma Cancer Stem Cells: An Overview
P2860
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P2860
The synovial sarcoma-associated SYT-SSX2 oncogene antagonizes the polycomb complex protein Bmi1.
description
2009 nî lūn-bûn
@nan
2009 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@ast
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@en
type
label
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@ast
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@en
prefLabel
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@ast
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@en
P2093
P2860
P1433
P1476
The synovial sarcoma-associate ...... polycomb complex protein Bmi1.
@en
P2093
Christina B Garcia
Josiane E Eid
P2860
P356
10.1371/JOURNAL.PONE.0005060
P407
P577
2009-04-01T00:00:00Z