Altered subcellular distribution of c-Abl in Alzheimer's disease.
about
c-Abl phosphorylates α-synuclein and regulates its degradation: implication for α-synuclein clearance and contribution to the pathogenesis of Parkinson's diseaseMultifunctional Abl kinases in health and diseaseEphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomersOxidative stress, mitochondrial damage and neurodegenerative diseasesAltered distribution of the EphA4 kinase in hippocampal brain tissue of patients with Alzheimer's disease correlates with pathologyTyrosine Kinase Inhibition Regulates Early Systemic Immune Changes and Modulates the Neuroimmune Response in α-SynucleinopathyRole of zinc metallothionein-3 (ZnMt3) in epidermal growth factor (EGF)-induced c-Abl protein activation and actin polymerization in cultured astrocytes.Neuronal c-Abl overexpression leads to neuronal loss and neuroinflammation in the mouse forebrain.Inhibition of Src kinase activity attenuates amyloid associated microgliosis in a murine model of Alzheimer's disease.Neuronal c-Abl activation leads to induction of cell cycle and interferon signaling pathwaysParkinson's disease: a complex interplay of mitochondrial DNA alterations and oxidative stress.c-Abl in neurodegenerative diseaseOxidative Stress, DNA Damage, and c-Abl Signaling: At the Crossroad in Neurodegenerative Diseases?Tyrosine Kinase Inhibitor as a new Therapy for Ischemic Stroke and other Neurologic Diseases: is there any Hope for a Better Outcome?Saitohin, which is nested within the tau gene, interacts with tau and Abl and its human-specific allele influences Abl phosphorylation.Granulovacuolar degeneration: a neurodegenerative change that accompanies tau pathology.Tau phosphorylated at tyrosine 394 is found in Alzheimer's disease tangles and can be a product of the Abl-related kinase, Arg.Tyrosine kinase inhibition increases functional parkin-Beclin-1 interaction and enhances amyloid clearance and cognitive performance.Nilotinib reverses loss of dopamine neurons and improves motor behavior via autophagic degradation of α-synuclein in Parkinson's disease models.Derailed intraneuronal signalling drives pathogenesis in sporadic and familial Alzheimer's disease.The Src/c-Abl pathway is a potential therapeutic target in amyotrophic lateral sclerosis.Reduction of Blood Amyloid-β Oligomers in Alzheimer's Disease Transgenic Mice by c-Abl Kinase Inhibition.Involvement of c-Abl Kinase in Microglial Activation of NLRP3 Inflammasome and Impairment in Autolysosomal System.The DNA Damage Response in Neurons: Die by Apoptosis or Survive in a Senescence-Like State?
P2860
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P2860
Altered subcellular distribution of c-Abl in Alzheimer's disease.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@ast
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@en
type
label
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@ast
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@en
prefLabel
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@ast
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@en
P2093
P2860
P356
P1476
Altered subcellular distribution of c-Abl in Alzheimer's disease.
@en
P2093
John Caltagarone
Robert Bowser
Zheng Jing
P2860
P304
P356
10.3233/JAD-2009-1062
P577
2009-01-01T00:00:00Z