about
Synthetic Peptides as Protein MimicsExpanding the number of 'druggable' targets: non-enzymes and protein-protein interactionsTransmembrane signal transduction by peptide hormones via family B G protein-coupled receptorsServerification of molecular modeling applications: the Rosetta Online Server that Includes Everyone (ROSIE)Medicinal chemistry as a conduit for the modulation of quorum sensing.The Privileged Chemical Space Predictor (PCSP): a computer program that identifies privileged chemical space from screens of modularly assembled chemical libraries.Rationally designed peptoids modulate aggregation of amyloid-beta 40.On-bead combinatorial synthesis and imaging of chemical exchange saturation transfer magnetic resonance imaging agents to identify factors that influence water exchange.Development of homomultimers and heteromultimers of lung cancer-specific peptoids.A biomimetic polyketide-inspired approach to small-molecule ligand discovery.Peptoid-Peptide hybrid ligands targeting the polo box domain of polo-like kinase 1.Synthesis of libraries of peptidomimetic compounds containing a 2-oxopiperazine unit in the main chain.Aβ42-binding peptoids as amyloid aggregation inhibitors and detection ligands.Synthesis and screening of stereochemically diverse combinatorial libraries of peptide tertiary amides.A readily applicable strategy to convert peptides to peptoid-based therapeutics.Expanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease.Synthesis and Characterization of Amphiphilic Cyclic Diblock Copolypeptoids from N-Heterocyclic Carbene-Mediated Zwitterionic Polymerization of N-Substituted N-carboxyanhydride.New Frontiers in DruggabilityUnbiased Selection of Peptide-Peptoid Hybrids Specific for Lung Cancer Compared to Normal Lung Epithelial Cells.Solid-phase submonomer synthesis of peptoid polymers and their self-assembly into highly-ordered nanosheets.Development of Peptoid-Based Ligands for the Removal of Cadmium from Biological Media.Cyclization of peptoids by formation of boronate esters.Development of a large peptoid-DOTA combinatorial library.In vivo biodistribution and small animal PET of (64)Cu-labeled antimicrobial peptoids.A chemically synthesized peptoid-based drag-tag enhances free-solution DNA sequencing by capillary electrophoresis.Novel C6-substituted 1,3,4-oxadiazinones as potential anti-cancer agents.A peptoid ribbon secondary structure.Identification of lipid-phosphatidylserine (PS) as the target of unbiasedly selected cancer specific peptide-peptoid hybrid PPS1.Rational design of chemical genetic probes of RNA function and lead therapeutics targeting repeating transcripts.Molecules that mimic apolipoprotein A-I: potential agents for treating atherosclerosis.Extraordinarily robust polyproline type I peptoid helices generated via the incorporation of α-chiral aromatic N-1-naphthylethyl side chains.γ-AApeptides as a New Class of Peptidomimetics.Macrocyclic peptoid-Peptide hybrids as inhibitors of class I histone deacetylases.Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents.Synthesis of the first examples of iminosugar clusters based on cyclopeptoid coresSynthesis of acylhydrazino-peptomers, a new class of peptidomimetics, by consecutive Ugi and hydrazino-Ugi reactionsDesign and conformational analysis of peptoids containing N-hydroxy amides reveals a unique sheet-like secondary structure.Library Design-Facilitated High-Throughput Sequencing of Synthetic Peptide Libraries.Linear peptidomimetics as potent antagonists of Staphylococcus aureus agr quorum sensing.Controlled synthesis of highly-branched plasmonic gold nanoparticles through peptoid engineering.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Peptoids as potential therapeutics.
@ast
Peptoids as potential therapeutics.
@en
type
label
Peptoids as potential therapeutics.
@ast
Peptoids as potential therapeutics.
@en
prefLabel
Peptoids as potential therapeutics.
@ast
Peptoids as potential therapeutics.
@en
P1476
Peptoids as potential therapeutics
@en
P2093
Ronald N Zuckermann
Thomas Kodadek
P304
P577
2009-06-01T00:00:00Z