May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
about
The May-Hegglin anomaly gene MYH9 is a negative regulator of platelet biogenesis modulated by the Rho-ROCK pathway.Fetal and neonatal thrombocytopenia.Recent advances in the understanding and management of MYH9-related inherited thrombocytopenias.The abnormal proplatelet formation in MYH9-related macrothrombocytopenia results from an increased actomyosin contractility and is rescued by myosin IIA inhibition.Myosin-II repression favors pre/proplatelets but shear activation generates platelets and fails in macrothrombocytopeniaEpidural anesthesia for labor and delivery in a patient with May-Hegglin anomaly: a case report.A new familial 'giant platelet syndrome' with structural, metabolic and functional abnormalities of platelets due to a primary megakaryocyte defect.Platelets of the Wistar Furth rat have reduced levels of alpha-granule proteins. An animal model resembling gray platelet syndrome.Of mice and men: Relevance of cellular and molecular characterizations of myosin IIA to MYH9-related human disease.The organization of microtubules and microtubule coils in giant platelet disorders.Single-platelet nanomechanics measured by high-throughput cytometry.
P2860
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P2860
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
description
1974 nî lūn-bûn
@nan
1974 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
1974 թվականի հունվարին հրատարակված գիտական հոդված
@hy
1974年の論文
@ja
1974年論文
@yue
1974年論文
@zh-hant
1974年論文
@zh-hk
1974年論文
@zh-mo
1974年論文
@zh-tw
1974年论文
@wuu
name
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@ast
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@en
type
label
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@ast
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@en
prefLabel
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@ast
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@en
P1476
May-Hegglin anomaly: a defect in megakaryocyte fragmentation?
@en
P2093
Ginsburg AD
P304
P356
10.1111/J.1365-2141.1974.TB00455.X
P407
P577
1974-01-01T00:00:00Z