Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression
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Current perspectives on the immunopathogenesis of systemic sclerosisPathobiology of pulmonary arterial hypertension and right ventricular failureImmunoregulatory molecules are master regulators of inflammation during the immune responseCellular Therapies in Systemic Sclerosis: Recent ProgressBlocking macrophage leukotriene b4 prevents endothelial injury and reverses pulmonary hypertension.Proteome-wide analysis and CXCL4 as a biomarker in systemic sclerosisIloprost modulates the immune response in systemic sclerosis.Inflammation and immunity in the pathogenesis of pulmonary arterial hypertensionEffect of Th17 and Treg axis disorder on outcomes of pulmonary arterial hypertension in connective tissue diseasesTumor cell lysate induces the immunosuppression and apoptosis of mouse immunocytes.Elevated levels of CD4(+)CD25(+)FoxP3(+) T cells in systemic sclerosis patients contribute to the secretion of IL-17 and immunosuppression dysfunction.Review: interstitial lung disease associated with systemic sclerosis and idiopathic pulmonary fibrosis: how similar and distinct?Intracellular free radical production by peripheral blood T lymphocytes from patients with systemic sclerosis: role of NADPH oxidase and ERK1/2.Vascular involvement in systemic sclerosis (scleroderma).Semaphorin 7a+ regulatory T cells are associated with progressive idiopathic pulmonary fibrosis and are implicated in transforming growth factor-β1-induced pulmonary fibrosis.Assessment of T regulatory cells and expanded profiling of autoantibodies may offer novel biomarkers for the clinical management of systemic sclerosis and undifferentiated connective tissue disease.TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients.Increased frequency of Th17 cells in systemic sclerosis is related to disease activity and collagen overproduction.Autoimmune mechanisms of scleroderma and a role of oxidative stress.T cells in systemic sclerosis: a reappraisal.Is CD69 an effective brake to control inflammatory diseases?The sex bias in systemic sclerosis: on the possible mechanisms underlying the female disease preponderance.Radiological thymus alterations in systemic sclerosis: our experience and a review of the literature.Transforming growth factor β--at the centre of systemic sclerosis.Interleukin-6: a new therapeutic target in systemic sclerosis?Current frontiers in systemic sclerosis pathogenesis.Interstitial lung disease in systemic sclerosis: current and future treatment.Regulatory T Cells in Systemic Sclerosis: a Comprehensive Review.Regulatory T cells limit vascular endothelial injury and prevent pulmonary hypertension.Crucial role for CD69 in allergic inflammatory responses: CD69-Myl9 system in the pathogenesis of airway inflammation.A system out of breath: how hypoxia possibly contributes to the pathogenesis of systemic sclerosis.Treg/Th17 cell balance and phytohaemagglutinin activation of T lymphocytes in peripheral blood of systemic sclerosis patients.Maintenance of immune tolerance by Foxp3+ regulatory T cells requires CD69 expression.Human intrahepatic regulatory T cells are functional, require IL-2 from effector cells for survival, and are susceptible to Fas ligand-mediated apoptosisMesenchymal stem cells (MSCs) from scleroderma patients (SSc) preserve their immunomodulatory properties although senescent and normally induce T regulatory cells (Tregs) with a functional phenotype: implications for cellular-based therapy.Exosomes with membrane-associated TGF-β1 from gene-modified dendritic cells inhibit murine EAE independently of MHC restriction.Peripheral blood regulatory T cells in patients with diffuse systemic sclerosis (SSc) before and after autologous hematopoietic SCT: a pilot study.Human neurocysticercosis: in vivo expansion of peripheral regulatory T cells and their recruitment in the central nervous system.Preterm neonates show marked leukopenia and lymphopenia that are associated with increased regulatory T-cell values and diminished IL-7.Unmet Needs in Systemic Sclerosis Understanding and Treatment: the Knowledge Gaps from a Scientist's, Clinician's, and Patient's Perspective.
P2860
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P2860
Increased frequency and compromised function of T regulatory cells in systemic sclerosis (SSc) is related to a diminished CD69 and TGFbeta expression
description
2009 nî lūn-bûn
@nan
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@ast
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@en
type
label
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@ast
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@en
prefLabel
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@ast
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@en
P2093
P2860
P1433
P1476
Increased frequency and compro ...... ed CD69 and TGFbeta expression
@en
P2093
Anila Hussaini
Jasper Broen
Kim Santegoets
Lenny van Bon
Mark Wenink
Timothy R D J Radstake
William W Cruikshank
Yanhui Deng
P2860
P356
10.1371/JOURNAL.PONE.0005981
P407
P577
2009-06-22T00:00:00Z