Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia - Wikidata - wikimedia - TriplyDB

Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

http://www.wikidata.org/entity/Q33476352

about

Drug-induced and drug-dependent immune thrombocytopenias.Patients with quinine-induced immune thrombocytopenia have both "drug-dependent" and "drug-specific" antibodies.Fine specificity of drug-dependent antibodies reactive with a restricted domain of platelet GPIIIA Quinine-dependent, platelet-reactive monoclonals mimic antibodies found in patients with quinine-induced immune thrombocytopenia Drug-induced immune thrombocytopenia: pathogenesis, diagnosis, and management Quinine-induced thrombocytopenia.Antibodies causing thrombocytopenia in patients treated with RGD-mimetic platelet inhibitors recognize ligand-specific conformers of αIIb/β3 integrin.A megakaryocyte with no platelets: anti-platelet antibodies, apoptosis, and platelet production.Mechanism of quinine-dependent monoclonal antibody binding to platelet glycoprotein IIb/IIIa.Antigenic differences between human platelets and megakaryocytes.Binding of quinine- and quinidine-dependent drug antibodies to platelets is mediated by the Fab domain of the immunoglobulin G and is not Fc dependent.Fab-mediated binding of drug-dependent antibodies to platelets in quinidine- and quinine-induced thrombocytopenia.Drug-induced immune thrombocytopenia: Mapping of the drug binding site to the membrane-proximal region of platelet GPIX.

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

http://www.wikidata.org/entity/Q33476352

description

1982 nî lūn-bûn

@nan

1982 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

1982 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

1982年の論文

@ja

1982年論文

@yue

1982年論文

@zh-hant

1982年論文

@zh-hk

1982年論文

@zh-mo

1982年論文

@zh-tw

1982年论文

@wuu

name

Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

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type

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

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Journal of Clinical Investigation

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Drug-antibody-platelet interaction in quinine- and quinidine-induced thrombocytopenia

@en

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D J Christie

http://www.w3.org/2001/XMLSchema#string

R H Aster

http://www.w3.org/2001/XMLSchema#string

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A modification of the Lowry procedure to simplify protein determination in membrane and lipoprotein samples

Immunoreactions involving platelets. I. A steric and kinetic model for formation of a complex from a human antibody, quinidine as a haptene, and platelets; and for fixation of complement by the complex.

Immunoreactions involving platelets. II. Theoretical analysis of the model

Immunoreactions involving platelets. IV. Studies on the pathogenesis of thrombocytopenia in drug purpura using test doses of quinidine in sensitized individuals; their implications in idiopathic thrombocytopenic purpura.

Immunologic reactions to drugs.

Quinine- and quinidine-dependent antiplatelet antibodies. Requirement of factor VIII-related antigen for platelet damage and for in vitro transformation of lymphocytes from patients with drug-induced thrombocytopenia

Direct quantitation of platelet-associated IgG by electroimmunoassay.

Drug-induced thrombocytopenia is associated with increased binding of IgG to platelets both in vivo and in vitro.

Study of the factors that cause specific transformation in cultures of lymphocytes from patients with quinine- and quinidine-induced immune thrombocytopenia

Relationship of raised platelet IgG in thrombocytopenia to total platelet protein content.

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989-998

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scholarly article

P356

10.1172/JCI110710

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5

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70

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1982-11-01T00:00:00Z

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6215430

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thrombocytopenia

P932

370311

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