Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A. - Wikidata - wikimedia - TriplyDB

Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A.

Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A.

http://www.wikidata.org/entity/Q33479860

about

Multiple ATR-Chk1 pathway proteins preferentially associate with checkpoint-inducing DNA substrates Nucleotide excision repair is associated with the replisome and its efficiency depends on a direct interaction between XPA and PCNA Phosphorylation: the molecular switch of double-strand break repair Skin cancer in organ transplant recipients: effects of immunosuppressive medications on DNA repair Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1 E2F1 localizes to sites of UV-induced DNA damage to enhance nucleotide excision repair.The oncogenic phosphatase WIP1 negatively regulates nucleotide excision repair Hydrogen peroxide induced genomic instability in nucleotide excision repair-deficient lymphoblastoid cells The DNA damage response kinases DNA-dependent protein kinase (DNA-PK) and ataxia telangiectasia mutated (ATM) Are stimulated by bulky adduct-containing DNA.Differential DNA damage responses in p53 proficient and deficient cells: cisplatin-induced nuclear import of XPA is independent of ATR checkpoint in p53-deficient lung cancer cells.The role of XPC: implications in cancer and oxidative DNA damage XPA-mediated regulation of global nucleotide excision repair by ATR Is p53-dependent and occurs primarily in S-phase.NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sites CDK2 and PKA mediated-sequential phosphorylation is critical for p19INK4d function in the DNA damage response Protein modification by adenine propenal Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair.A new structural insight into XPA-DNA interactions.UV-induced nuclear import of XPA is mediated by importin-α4 in an ATR-dependent manner The RASSF1A tumor suppressor regulates XPA-mediated DNA repair Tethering DNA damage checkpoint mediator proteins topoisomerase IIbeta-binding protein 1 (TopBP1) and Claspin to DNA activates ataxia-telangiectasia mutated and RAD3-related (ATR) phosphorylation of checkpoint kinase 1 (Chk1)PKA-mediated phosphorylation of ATR promotes recruitment of XPA to UV-induced DNA damage.Association of the XPA A23G polymorphism with the risk of head and neck carcinomas: Evidence from 5,491 subjects.AKAP12 mediates PKA-induced phosphorylation of ATR to enhance nucleotide excision repair Progerin sequestration of PCNA promotes replication fork collapse and mislocalization of XPA in laminopathy-related progeroid syndromes.The mechanism of nucleotide excision repair-mediated UV-induced mutagenesis in nonproliferating cells.Mitotic genes are transcriptionally upregulated in the fibroblast irradiated with very low doses of UV-C Mind the gap: keeping UV lesions in check.PTEN in DNA damage repair.DNA damage response: three levels of DNA repair regulation.ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle.A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts.Reevaluation of ATR signaling in primary resting chronic lymphocytic leukemia cells: evidence for pro-survival or pro-apoptotic function.Xeroderma Pigmentosa Group A (XPA), Nucleotide Excision Repair and Regulation by ATR in Response to Ultraviolet Irradiation.Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes.Roles of UVA radiation and DNA damage responses in melanoma pathogenesis.

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Checkpoint kinase ATR promotes nucleotide excision repair of UV-induced DNA damage via physical interaction with xeroderma pigmentosum group A.

http://www.wikidata.org/entity/Q33479860

description

2009 nî lūn-bûn

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2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի հուլիսին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

@zh-hant

2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

Checkpoint kinase ATR promotes ...... xeroderma pigmentosum group A.

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Checkpoint kinase ATR promotes ...... xeroderma pigmentosum group A.

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Checkpoint kinase ATR promotes ...... xeroderma pigmentosum group A.

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Journal of Biological Chemistry

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P2093

Chris Brosey

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Nikolozi Shkriabai

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Phillip R Musich

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Steven M Shell

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Walter J Chazin

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Yue Zou

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P2860

Analysis of the XPA and ssDNA-binding surfaces on the central domain of human ERCC1 reveals evidence for subfunctionalization

Electrostatics of nanosystems: application to microtubules and the ribosome

The comings and goings of nucleotide excision repair factors on damaged DNA

Interactions of human nucleotide excision repair protein XPA with DNA and RPA70 Delta C327: chemical shift mapping and 15N NMR relaxation studies

Structural basis for the recognition of DNA repair proteins UNG2, XPA, and RAD52 by replication factor RPA

Structural basis for the recruitment of ERCC1-XPF to nucleotide excision repair complexes by XPA

Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

PDB2PQR: an automated pipeline for the setup of Poisson-Boltzmann electrostatics calculations

The DNA damage response: putting checkpoints in perspective

Prediction of the secondary structure of proteins from their amino acid sequence

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284

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Moises A Serrano

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19586908

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2782015

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