Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action.
about
Sensory detection and responses to toxic gases: mechanisms, health effects, and countermeasures.Metabolism of styrene to styrene oxide and vinylphenols in cytochrome P450 2F2- and P450 2E1-knockout mouse liver and lung microsomesRole of metabolic activation and the TRPA1 receptor in the sensory irritation response to styrene and naphthalene.Detection of phenolic metabolites of styrene in mouse liver and lung microsomal incubations.Evaluation of the carcinogenicity of inorganic arsenic.An RNA-seq protocol to identify mRNA expression changes in mouse diaphyseal bone: applications in mice with bone property altering Lrp5 mutationsDisposition and metabolism of cumene in F344 rats and B6C3F1 mice.Comparative pathobiology of environmentally induced lung cancers in humans and rodents.Generation and characterization of a Cyp2f2-null mouse and studies on the role of CYP2F2 in naphthalene-induced toxicity in the lung and nasal olfactory mucosaRelationship of metabolism and cell proliferation to the mode of action of fluensulfone-induced mouse lung tumors: analysis of their human relevance using the IPCS framework.Hypothesis-based weight-of-evidence evaluation and risk assessment for naphthalene carcinogenesis.Hypothesis-based weight of evidence: a tool for evaluating and communicating uncertainties and inconsistencies in the large body of evidence in proposing a carcinogenic mode of action--naphthalene as an example.Characterization of the toxicological hazards of hydrocarbon solvents.Risk assessments for chronic exposure of children and prospective parents to ethylbenzene (CAS No. 100-41-4).An Evaluation of the Human Relevance of the Lung Tumors Observed in Female Mice Treated With Permethrin Based on Mode of Action.Xenobiotic metabolism in differentiated human bronchial epithelial cells.Relationship of Metabolism and Cell Proliferation to the Mode of Action of Fluensulfone-Induced Mouse Lung Tumors. II: Additional Mechanistic Studies.Garlic capsule and selenium-vitamins ACE combination therapy modulate key antioxidant proteins and cellular adenosine triphosphate in lisinopril-induced lung damage in rats.Editor's Highlight: Complete Attenuation of Mouse Lung Cell Proliferation and Tumorigenicity in CYP2F2 Knockout and CYP2F1 Humanized Mice Exposed to Inhaled Styrene for up to 2 Years Supports a Lack of Human Relevance.
P2860
Q27693846-5A9D7AC0-6004-407E-BDE0-4A13CA13F6EDQ28387070-F87AD27A-0D40-4A89-8497-620DFD9E553BQ34169548-60EB8C24-4BE6-4502-9F99-A8B3E2808F03Q34257476-02F58FF8-FEEB-41D7-8BFB-967B1D5ED0E2Q34371580-628DD657-0D89-4A59-B053-FD8AC5905C5FQ34647373-B89144BF-85E9-4922-86D6-B5CA1F77B818Q34702549-C913D313-EA4B-45E4-BBF0-8430917BEA26Q35027707-2708EE56-009D-440F-9467-5D098D56F260Q35265554-B34FBA21-F498-47F1-9FD6-674BE45605C9Q36080030-B433914D-D3EC-4C3B-AFD4-B3A85280271EQ36518971-02222E10-8FA8-42A0-A2D4-0E588BD8C01BQ37781056-B40DC9E4-D8C2-418F-B0C7-97FE361B8B8FQ38418527-EABB73AA-B0BF-4B69-8945-B885ED90B318Q38495604-F5B732E5-EDE7-49B0-A189-D19C4DC3C12CQ38826418-153D6D63-06EA-48EF-8539-D961FB25446CQ39293415-B607D26B-7161-407B-BD4A-E89F8870F3B8Q39412227-6E76F3AB-04FF-45CC-8BC5-16D0D1357355Q51542156-8D8570FB-2FB0-4281-9C0B-C3FB2DBED918Q53052935-7AEF3BAF-4413-4196-9DE3-9D92A3D07541
P2860
Mouse specific lung tumors from CYP2F2-mediated cytotoxic metabolism: an endpoint/toxic response where data from multiple chemicals converge to support a mode of action.
description
2009 nî lūn-bûn
@nan
2009 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Mouse specific lung tumors fro ...... e to support a mode of action.
@ast
Mouse specific lung tumors fro ...... e to support a mode of action.
@en
type
label
Mouse specific lung tumors fro ...... e to support a mode of action.
@ast
Mouse specific lung tumors fro ...... e to support a mode of action.
@en
prefLabel
Mouse specific lung tumors fro ...... e to support a mode of action.
@ast
Mouse specific lung tumors fro ...... e to support a mode of action.
@en
P2093
P1476
Mouse specific lung tumors fro ...... e to support a mode of action.
@en
P2093
Gary Carlson
George Cruzan
Marcy Banton
Ralph Gingell
P304
P356
10.1016/J.YRTPH.2009.07.002
P407
P577
2009-07-07T00:00:00Z