Beyond the brain: widespread pathology in Huntington's disease.
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The choreography of neuroinflammation in Huntington's diseaseSystems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemN17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic miceHDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophyAltered hypothalamic protein expression in a rat model of Huntington's diseaseAmitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heartThe chicken or the egg: mitochondrial dysfunction as a cause or consequence of toxicity in Huntington's diseaseA broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.Huntington’s disease blood and brain show a common gene expression pattern and share an immune signature with Alzheimer’s diseaseProgressive and self-limiting neurodegenerative disorders in Africa: a new prominent field of research led by South Africa but without strong health policy.Mutant huntingtin impairs immune cell migration in Huntington disease.The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling.High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function.Age-associated chromatin relaxation is enhanced in Huntington's disease mice.Peripheral huntingtin silencing does not ameliorate central signs of disease in the B6.HttQ111/+ mouse model of Huntington's diseaseChanges of peripheral TGF-β1 depend on monocytes-derived macrophages in Huntington diseaseFull-length huntingtin levels modulate body weight by influencing insulin-like growth factor 1 expressionMetabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients.In vivo expression of polyglutamine-expanded huntingtin by mouse striatal astrocytes impairs glutamate transport: a correlation with Huntington's disease subjects.Abnormal peripheral chemokine profile in Huntington's diseaseTwo-point magnitude MRI for rapid mapping of brown adipose tissue and its application to the R6/2 mouse model of Huntington diseaseThe Huntington's disease-related cardiomyopathy prevents a hypertrophic response in the R6/2 mouse model.Preclinical and clinical investigations of mood stabilizers for Huntington's disease: what have we learned?Skeletal muscle pathology in Huntington's diseaseCharacterisation of immune cell function in fragment and full-length Huntington's disease mouse modelsAdipose Tissue Distribution Predicts Survival in Amyotrophic Lateral SclerosisA ketogenic diet delays weight loss and does not impair working memory or motor function in the R6/2 1J mouse model of Huntington's diseaseNeuronal expression of TATA box-binding protein containing expanded polyglutamine in knock-in mice reduces chaperone protein response by impairing the function of nuclear factor-Y transcription factor.Nitric oxide dysregulation in platelets from patients with advanced Huntington disease.An exploratory double-blind, randomized clinical trial with selisistat, a SirT1 inhibitor, in patients with Huntington's disease.Is Dysregulation of the HPA-Axis a Core Pathophysiology Mediating Co-Morbid Depression in Neurodegenerative Diseases?Dysfunction of the CNS-heart axis in mouse models of Huntington's disease.Transcriptional modulator H2A histone family, member Y (H2AFY) marks Huntington disease activity in man and mouseHigh Protein Diet and Huntington's DiseaseThree Huntington's Disease Specific Mutation-Carrying Human Embryonic Stem Cell Lines Have Stable Number of CAG Repeats upon In Vitro Differentiation into Cardiomyocytes.A 24-Hour Study of the Hypothalamo-Pituitary Axes in Huntington's Disease.Mutant Huntingtin Does Not Affect the Intrinsic Phenotype of Human Huntington's Disease T Lymphocytes.Characterization of Gastric Mucosa Biopsies Reveals Alterations in Huntington's Disease.Huntington's disease: Neural dysfunction linked to inositol polyphosphate multikinase.
P2860
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P2860
Beyond the brain: widespread pathology in Huntington's disease.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Beyond the brain: widespread pathology in Huntington's disease.
@ast
Beyond the brain: widespread pathology in Huntington's disease.
@en
type
label
Beyond the brain: widespread pathology in Huntington's disease.
@ast
Beyond the brain: widespread pathology in Huntington's disease.
@en
prefLabel
Beyond the brain: widespread pathology in Huntington's disease.
@ast
Beyond the brain: widespread pathology in Huntington's disease.
@en
P1433
P1476
Beyond the brain: widespread pathology in Huntington's disease.
@en
P2093
Jorien M M van der Burg
Maria Björkqvist
P304
P356
10.1016/S1474-4422(09)70178-4
P577
2009-08-01T00:00:00Z