A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response
about
Comprehensive molecular portraits of human breast tumoursCoordination of nutrient availability and utilization by MAX- and MLX-centered transcription networksA model of spontaneous mouse mammary tumor for human estrogen receptor- and progesterone receptor-negative breast cancerBreast cancer classification and prognostication through diverse systems along with recent emerging findings in this respect; the dawn of new perspectives in the clinical applications.Wnt signaling in triple negative breast cancer is associated with metastasisLive-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control.Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts.MYC Deregulation in Primary Human Cancers.Large-scale analysis of expression signatures reveals hidden links among diverse cellular processes.The action mechanism of the Myc inhibitor termed Omomyc may give clues on how to target Myc for cancer therapy.RNA interference (RNAi) screening approach identifies agents that enhance paclitaxel activity in breast cancer cells.Transcriptional amplification in tumor cells with elevated c-Myc.Claudin-low breast cancers: clinical, pathological, molecular and prognostic characterizationDifferential expression of aquaporins and its diagnostic utility in thyroid cancer.Hunk is required for HER2/neu-induced mammary tumorigenesis.The non-negative matrix factorization toolbox for biological data mining.Gene expression profiles of estrogen receptor-positive and estrogen receptor-negative breast cancers are detectable in histologically normal breast epitheliumAn integrated genomics approach identifies drivers of proliferation in luminal-subtype human breast cancer.Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancersRB loss contributes to aggressive tumor phenotypes in MYC-driven triple negative breast cancer.Linking tumor mutations to drug responses via a quantitative chemical-genetic interaction map.Metabolic reprogramming in triple-negative breast cancer through Myc suppression of TXNIPGranulin, a novel STAT3-interacting protein, enhances STAT3 transcriptional function and correlates with poorer prognosis in breast cancer.snoRNAs are a novel class of biologically relevant Myc targets.Metabolic Signatures of Human Breast Cancer.MYC is expressed in the stromal and epithelial cells of primary breast carcinoma and paired nodal metastases.MYC pathway activation in triple-negative breast cancer is synthetic lethal with CDK inhibitionβ-catenin regulates c-Myc and CDKN1A expression in breast cancer cells.Anti-protozoal and anti-bacterial antibiotics that inhibit protein synthesis kill cancer subtypes enriched for stem cell-like properties.Small molecule inhibitors of IRES-mediated translation.Taking on challenging targets: making MYC druggable.MYC Is a Crucial Mediator of TGFβ-Induced Invasion in Basal Breast Cancer.The SOX11 transcription factor is a critical regulator of basal-like breast cancer growth, invasion, and basal-like gene expression.Control of vertebrate development by MYCMYC and transcription elongation.MYC-driven accumulation of 2-hydroxyglutarate is associated with breast cancer prognosis.Targeting cyclin-dependent kinase 1 (CDK1) but not CDK4/6 or CDK2 is selectively lethal to MYC-dependent human breast cancer cells.Contribution of serine, folate and glycine metabolism to the ATP, NADPH and purine requirements of cancer cellsGlutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target
P2860
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P2860
A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
name
A core MYC gene expression sig ...... erlaps the core serum response
@ast
A core MYC gene expression sig ...... erlaps the core serum response
@en
type
label
A core MYC gene expression sig ...... erlaps the core serum response
@ast
A core MYC gene expression sig ...... erlaps the core serum response
@en
prefLabel
A core MYC gene expression sig ...... erlaps the core serum response
@ast
A core MYC gene expression sig ...... erlaps the core serum response
@en
P2860
P50
P1433
P1476
A core MYC gene expression sig ...... erlaps the core serum response
@en
P2093
Michael D Cole
Michael L Whitfield
P2860
P356
10.1371/JOURNAL.PONE.0006693
P407
P577
2009-08-19T00:00:00Z