Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling.
about
The multitargeted receptor tyrosine kinase inhibitor linifanib (ABT-869) induces apoptosis through an Akt and glycogen synthase kinase 3β-dependent pathway.Animal models in the drug discovery pipeline for Alzheimer's diseaseHematopoietic stem cells, hematopoiesis and disease: lessons from the zebrafish modelSmall-Molecule Inhibitors of GSK-3: Structural Insights and Their Application to Alzheimer's Disease ModelsMiR-744 increases tumorigenicity of pancreatic cancer by activating Wnt/β-catenin pathway.Presenilins regulate neurotrypsin gene expression and neurotrypsin-dependent agrin cleavage via cyclic AMP response element-binding protein (CREB) modulationOne step forward: the use of transgenic zebrafish tumor model in drug screens.Unraveling protein misfolding diseases using model systemsAlteration of 11β-hydroxysteroid dehydrogenase type 1 and glucocorticoid receptor by ethanol in rat liver and mouse hepatoma cells.Ketamine Increases Permeability and Alters Epithelial Phenotype of Renal Distal Tubular Cells via a GSK-3β-Dependent Mechanism.Dissecting the differentiation process of the preplacodal ectoderm in zebrafish.LX2343 alleviates cognitive impairments in AD model rats by inhibiting oxidative stress-induced neuronal apoptosis and tauopathy.Investigation of naphthofuran moiety as potential dual inhibitor against BACE-1 and GSK-3β: molecular dynamics simulations, binding energy, and network analysis to identify first-in-class dual inhibitors against Alzheimer's disease.
P2860
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P2860
Characterization and development of novel small-molecules inhibiting GSK3 and activating Wnt signaling.
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Characterization and developme ...... and activating Wnt signaling.
@ast
Characterization and developme ...... and activating Wnt signaling.
@en
type
label
Characterization and developme ...... and activating Wnt signaling.
@ast
Characterization and developme ...... and activating Wnt signaling.
@en
prefLabel
Characterization and developme ...... and activating Wnt signaling.
@ast
Characterization and developme ...... and activating Wnt signaling.
@en
P2093
P2860
P356
P1433
P1476
Characterization and developme ...... and activating Wnt signaling.
@en
P2093
Deborah Moshinsky
Haigen Huang
Haixia Zou
Hanbing Zhong
Junmin Quan
Mikhail V Semenov
P2860
P304
P356
10.1039/B905752H
P50
P577
2009-08-12T00:00:00Z