Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
about
Engineering Hydrophobic Protein–Carbohydrate Interactions to Fine-Tune Monoclonal AntibodiesRestricted motion of the conserved immunoglobulin G1 N-glycan is essential for efficient FcγRIIIa binding.Production of α2,6-sialylated IgG1 in CHO cellsNMR characterization of immunoglobulin G Fc glycan motion on enzymatic sialylation.Stabilizing the CH2 Domain of an Antibody by Engineering in an Enhanced Aromatic SequonMetabolic oligosaccharide engineering: implications for selectin-mediated adhesion and leukocyte extravasation.Consequences of glycan truncation on Fc structural integrity.State-of-the-art technologies for rapid and high-throughput sample preparation and analysis of N-glycans from antibodies.Rational design of therapeutic mAbs against aggregation through protein engineering and incorporation of glycosylation motifs applied to bevacizumabGlycosylation of IgG-Fc: a molecular perspective.The impact of glycosylation on monoclonal antibody conformation and stability.NMR analysis demonstrates immunoglobulin G N-glycans are accessible and dynamic.Impact of deglycosylation and thermal stress on conformational stability of a full length murine IgG2a monoclonal antibody: observations from molecular dynamics simulations.Heat denaturation of the antibody, a multi-domain protein.Engineering of Fc Fragments with Optimized Physicochemical Properties Implying Improvement of Clinical Potentials for Fc-Based Therapeutics.
P2860
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P2860
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@ast
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@en
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@nl
type
label
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@ast
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@en
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@nl
prefLabel
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@ast
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@en
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@nl
P2093
P2860
P1433
P1476
Dynamic fluctuations of protein-carbohydrate interactions promote protein aggregation.
@en
P2093
Bernhard Helk
Bernhardt L Trout
Cornelius Fritsch
Heidi Zhang
Holger Heine
Kurt Forrer
Naresh Chennamsetty
Veysel Kayser
Vladimir Voynov
P2860
P356
10.1371/JOURNAL.PONE.0008425
P407
P577
2009-12-23T00:00:00Z