LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease
about
Apolipoprotein E-low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner.Alzheimer amyloid beta inhibition of Eg5/kinesin 5 reduces neurotrophin and/or transmitter receptor function.Hsc70 rapidly engages tau after microtubule destabilizationMitotic spindle defects and chromosome mis-segregation induced by LDL/cholesterol-implications for Niemann-Pick C1, Alzheimer's disease, and atherosclerosis.The Hsp90 kinase co-chaperone Cdc37 regulates tau stability and phosphorylation dynamics.DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau.Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein SynthesisIdentification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain.Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradationLinking hypothetical knowledge patterns to disease molecular signatures for biomarker discovery in Alzheimer's disease.Role of Trisomy 21 Mosaicism in Sporadic and Familial Alzheimer's Disease.Characterization of proprotein convertase subtilisin/kexin type 9 (PCSK9) trafficking reveals a novel lysosomal targeting mechanism via amyloid precursor-like protein 2 (APLP2).Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative DiseasesCyclic cis-Locked Phospho-Dipeptides Reduce Entry of AβPP into Amyloidogenic Processing Pathway.Microsome Isolation from Tissue.Apolipoprotein e: essential catalyst of the Alzheimer amyloid cascade.Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach.
P2860
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P2860
LDLR expression and localization are altered in mouse and human cell culture models of Alzheimer's disease
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年学术文章
@wuu
2010年学术文章
@zh-cn
2010年学术文章
@zh-hans
2010年学术文章
@zh-my
2010年学术文章
@zh-sg
2010年學術文章
@yue
name
LDLR expression and localizati ...... models of Alzheimer's disease
@ast
LDLR expression and localizati ...... models of Alzheimer's disease
@en
LDLR expression and localizati ...... models of Alzheimer's disease.
@nl
type
label
LDLR expression and localizati ...... models of Alzheimer's disease
@ast
LDLR expression and localizati ...... models of Alzheimer's disease
@en
LDLR expression and localizati ...... models of Alzheimer's disease.
@nl
prefLabel
LDLR expression and localizati ...... models of Alzheimer's disease
@ast
LDLR expression and localizati ...... models of Alzheimer's disease
@en
LDLR expression and localizati ...... models of Alzheimer's disease.
@nl
P2093
P2860
P1433
P1476
LDLR expression and localizati ...... models of Alzheimer's disease
@en
P2093
Huntington Potter
Inge Wefes
Jaya Padmanabhan
Jose F Abisambra
Peter Neame
Tina Fiorelli
P2860
P356
10.1371/JOURNAL.PONE.0008556
P407
P577
2010-01-01T00:00:00Z