Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes. - Wikidata - wikimedia - TriplyDB

Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.

Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.

http://www.wikidata.org/entity/Q33525570

about

Stretch-activated ion channels: what are they?2015 Clinical trials update in sickle cell anemia Loss-of-function and gain-of-function phenotypes of stomatocytosis mutant RhAG F65S Mechanical dynamics in live cells and fluorescence-based force/tension sensors Molecular force transduction by ion channels: diversity and unifying principles.Inhibition of the K+ channel K(Ca)3.1 reduces TGF-β1-induced premature senescence, myofibroblast phenotype transition and proliferation of mesangial cells.MP4CO, a pegylated hemoglobin saturated with carbon monoxide, is a modulator of HO-1, inflammation, and vaso-occlusion in transgenic sickle mice.Dehydrated hereditary stomatocytosis linked to gain-of-function mutations in mechanically activated PIEZO1 ion channels Piezo proteins: regulators of mechanosensation and other cellular processes Functional characterization and modified rescue of novel AE1 mutation R730C associated with overhydrated cation leak stomatocytosis.N-ethylmaleimide activates a Cl(-)-independent component of K(+) flux in mouse erythrocytes Calcium in red blood cells-a perilous balance.Piezo1: properties of a cation selective mechanical channel Piezo channels and GsMTx4: Two milestones in our understanding of excitatory mechanosensitive channels and their role in pathology.The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso-occlusive crises.N-methyl-D-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation.Gating the mechanical channel Piezo1: a comparison between whole-cell and patch recording.Hereditary xerocytosis revisited Harnessing red cell membrane pathophysiology towards point-of-care diagnosis for sickle cell disease.Disorders of erythrocyte hydration.On the Mechanism of Human Red Blood Cell Longevity: Roles of Calcium, the Sodium Pump, PIEZO1, and Gardos Channels.Mechanical Transduction and the Dark Energy of Biology.Red blood cells of sickle cell disease patients exhibit abnormally high abundance of N-methyl D-aspartate receptors mediating excessive calcium uptake.The conductance of red blood cells from sickle cell patients: ion selectivity and inhibitors.

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P2860

Hypoxia activates a Ca2+-permeable cation conductance sensitive to carbon monoxide and to GsMTx-4 in human and mouse sickle erythrocytes.

http://www.wikidata.org/entity/Q33525570

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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JOURNAL.PONE.0008732

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Hypoxia activates a Ca2+-perme ...... and mouse sickle erythrocytes.

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Boris E Shmukler

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David H Vandorpe

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Frederick Sachs

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Marie Trudel

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Seth L Alper

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P2860

Identification of a peptide toxin from Grammostola spatulata spider venom that blocks cation-selective stretch-activated channels

Mechanosensitive ion channels and the peptide inhibitor GsMTx-4: history, properties, mechanisms and pharmacology

Monovalent cation leaks in human red cells caused by single amino-acid substitutions in the transport domain of the band 3 chloride-bicarbonate exchanger, AE1

Red blood cells induce hypoxic lung inflammation

Calcium-activated potassium channels in human platelets

Endothelin receptor antagonism prevents hypoxia-induced mortality and morbidity in a mouse model of sickle-cell disease.

Effects of deoxygenation on active and passive Ca2+ transport and on the cytoplasmic Ca2+ levels of sickle cell anemia red cells.

Treatment with oral clotrimazole blocks Ca(2+)-activated K+ transport and reverses erythrocyte dehydration in transgenic SAD mice. A model for therapy of sickle cell disease.

Understanding the shape of sickled red cells

Efficacy and safety of the Gardos channel blocker, senicapoc (ICA-17043), in patients with sickle cell anemia.

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scholarly article

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10.1371/JOURNAL.PONE.0008732

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1

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Philip A. Gottlieb

Leo E Otterbein

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2010-01-15T00:00:00Z

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41103267

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20090940

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carbon monoxide

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