Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease. - Wikidata - wikimedia - TriplyDB

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

http://www.wikidata.org/entity/Q33536124

about

The role of free radicals in the aging brain and Parkinson's Disease: convergence and parallelism Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease NRF2-regulation in brain health and disease: implication of cerebral inflammation Genetic Variations and mRNA Expression of NRF2 in Parkinson's Disease.NRF2 activation restores disease related metabolic deficiencies in olfactory neurosphere-derived cells from patients with sporadic Parkinson's disease Hydrogen peroxide responsive miR153 targets Nrf2/ARE cytoprotection in paraquat induced dopaminergic neurotoxicity.SKN-1/Nrf2 inhibits dopamine neuron degeneration in a Caenorhabditis elegans model of methylmercury toxicity.The endotoxin-induced neuroinflammation model of Parkinson's disease.Association of Nrf2 polymorphism haplotypes with acute lung injury phenotypes in inbred strains of mice.Genetic associations of Nrf2-encoding NFE2L2 variants with Parkinson's disease - a multicenter study.Genetic activation of Nrf2 signaling is sufficient to ameliorate neurodegenerative phenotypes in a Drosophila model of Parkinson's disease.Comprehensive assessment of genetic sequence variants in the antioxidant 'master regulator' NRF2 in idiopathic Parkinson's disease.Relationship between air pollution, NFE2L2 gene polymorphisms and childhood asthma in a Hungarian population.RBM45 Modulates the Antioxidant Response in Amyotrophic Lateral Sclerosis through Interactions with KEAP1.Thiol-redox signaling, dopaminergic cell death, and Parkinson's disease Nrf2--a therapeutic target for the treatment of neurodegenerative diseases.Genetic Polymorphisms of Transcription Factor NRF2 and of its Host Gene Sulfiredoxin (SRXN1) are Associated with Cerebrovascular Disease in a Finnish Cohort, the TAMRISK Study NFE2L2 variations reduce antioxidant response in patients with Parkinson disease.Genomic structure and variation of nuclear factor (erythroid-derived 2)-like 2 Repurposing the NRF2 Activator Dimethyl Fumarate as Therapy Against Synucleinopathy in Parkinson's Disease Lack of association between nuclear factor erythroid-derived 2-like 2 promoter gene polymorphisms and oxidative stress biomarkers in amyotrophic lateral sclerosis patients.Brain rust: recent discoveries on the role of oxidative stress in neurodegenerative diseases.P62/SQSTM1 at the interface of aging, autophagy, and disease.Antioxidative defense mechanisms controlled by Nrf2: state-of-the-art and clinical perspectives in neurodegenerative diseases.Nrf2: a modulator of Parkinson's disease?Pinocembrin attenuates 6-OHDA-induced neuronal cell death through Nrf2/ARE pathway in SH-SY5Y cells.Sustained Effects of Neonatal Systemic Lipopolysaccharide on IL-1β and Nrf2 in Adult Rat Substantia Nigra Are Partly Normalized by a Spirulina-Enriched Diet.Promoter region variation in NFE2L2 influences susceptibility to ototoxicity in patients exposed to high cumulative doses of cisplatin.Polydatin inhibits mast cell-mediated allergic inflammation by targeting PI3K/Akt, MAPK, NF-κB and Nrf2/HO-1 pathways.Nrf2 mitigates LRRK2- and α-synuclein-induced neurodegeneration by modulating proteostasis.The Nrf2/ARE Pathway: A Promising Target to Counteract Mitochondrial Dysfunction in Parkinson's Disease.Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.Association of NFE2L2 and KEAP1 haplotypes with amyotrophic lateral sclerosis.Hydralazine induces stress resistance and extends C. elegans lifespan by activating the NRF2/SKN-1 signalling pathway.Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease.α-Synuclein expression and Nrf2 deficiency cooperate to aggravate protein aggregation, neuronal death and inflammation in early-stage Parkinson's disease.A Novel Compound ITC-3 Activates the Nrf2 Signaling and Provides Neuroprotection in Parkinson's Disease Models.Deficiency in the transcription factor NRF2 worsens inflammatory parameters in a mouse model with combined tauopathy and amyloidopathy.

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Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

http://www.wikidata.org/entity/Q33536124

description

2010 nî lūn-bûn

@nan

2010 թուականի Մարտին հրատարակուած գիտական յօդուած

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2010 թվականի մարտին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

@zh-tw

2010年论文

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name

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@ast

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@en

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@nl

type

label

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@ast

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@en

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@nl

prefLabel

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@ast

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@en

Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

@nl

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1471-2350-11-36

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BMC Medical Genetics

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Association of Nrf2-encoding NFE2L2 haplotypes with Parkinson's disease.

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Anna Håkansson

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Dragana Celojevic

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Hans Nissbrandt

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Malin von Otter

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Mateusz Kurzawski

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Monika Bialecka

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Ola Hammarsten

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Petra Bergström

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Sara Landgren

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P2860

DJ-1, a cancer- and Parkinson's disease-associated protein, stabilizes the antioxidant transcriptional master regulator Nrf2

Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism

High-resolution whole-genome association study of Parkinson disease.

BTB protein Keap1 targets antioxidant transcription factor Nrf2 for ubiquitination by the Cullin 3-Roc1 ligase

Keap1 is a redox-regulated substrate adaptor protein for a Cul3-dependent ubiquitin ligase complex.

Oxidative stress sensor Keap1 functions as an adaptor for Cul3-based E3 ligase to regulate proteasomal degradation of Nrf2

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

The structure of haplotype blocks in the human genome

The International HapMap Project

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1471-2350-11-36

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36

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scholarly article

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10.1186/1471-2350-11-36

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11

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Staffan Nilsson

Henrik Zetterberg

Michael Nilsson

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2010-03-02T00:00:00Z

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41668657

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1036758606

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20196834

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Parkinson's disease

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2843602

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