Luminal loop of the ryanodine receptor: a pore-forming segment?
about
Structural aspects of calcium-release activated calcium channel functionCoordinated movement of cytoplasmic and transmembrane domains of RyR1 upon gatingPhylogeny of Na+/Ca2+ exchanger (NCX) genes from genomic data identifies new gene duplications and a new family member in fish species.A structural model of the pore-forming region of the skeletal muscle ryanodine receptor (RyR1)Pore dynamics and conductance of RyR1 transmembrane domain.Ryanodine receptors: structure, expression, molecular details, and function in calcium release.Evidence for a role of the lumenal M3-M4 loop in skeletal muscle Ca(2+) release channel (ryanodine receptor) activity and conductance.A model of the putative pore region of the cardiac ryanodine receptor channelNegatively charged amino acids within the intraluminal loop of ryanodine receptor are involved in the interaction with triadin.Probing the role of negatively charged amino acid residues in ion permeation of skeletal muscle ryanodine receptorTwo rings of negative charges in the cytosolic vestibule of type-1 ryanodine receptor modulate ion fluxes.Ryanodine receptor regulation by intramolecular interaction between cytoplasmic and transmembrane domains.Muscle weakness in Ryr1I4895T/WT knock-in mice as a result of reduced ryanodine receptor Ca2+ ion permeation and release from the sarcoplasmic reticulum.The ryanodine receptor in cardiac physiology and disease.Ca2+ release in muscle fibers expressing R4892W and G4896V type 1 ryanodine receptor disease mutantsPhylogeny and a structural model of plant MHX transportersFunctional characterization of the cardiac ryanodine receptor pore-forming region.Mild Clinical Features and Histopathologically Atypical Cores in Two Korean Families with Central Core Disease Harboring RYR1 Mutations at the C-Terminal RegionExcitation--contraction uncoupling by a human central core disease mutation in the ryanodine receptor.Internal structure and visualization of transmembrane domains of the RyR1 calcium release channel by cryo-EM.Functional effects of central core disease mutations in the cytoplasmic region of the skeletal muscle ryanodine receptorLocation of the permeation pathway in the recombinant type 1 inositol 1,4,5-trisphosphate receptor.Structural determinants of skeletal muscle ryanodine receptor gatingStructural insights into Ca(2+)-activated long-range allosteric channel gating of RyR1.Changes in negative charge at the luminal mouth of the pore alter ion handling and gating in the cardiac ryanodine-receptor.IP(3) receptors: toward understanding their activation.Ca2+ signaling in HEK-293 and skeletal muscle cells expressing recombinant ryanodine receptors harboring malignant hyperthermia and central core disease mutations.Targeting of inositol 1,4,5-trisphosphate receptors to the endoplasmic reticulum by multiple signals within their transmembrane domains.Functional characterization of mutants in the predicted pore region of the rabbit cardiac muscle Ca(2+) release channel (ryanodine receptor isoform 2).Three-dimensional structure of recombinant type 1 inositol 1,4,5-trisphosphate receptor.Structural understanding of the transmembrane domains of inositol triphosphate receptors and ryanodine receptors towards calcium channeling.Troponin I converts the skeletal muscle ryanodine receptor into a rectifying calcium release channel.The structural basis of ryanodine receptor ion channel function.Targeting and retention of type 1 ryanodine receptors to the endoplasmic reticulum.
P2860
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P2860
Luminal loop of the ryanodine receptor: a pore-forming segment?
description
1999 nî lūn-bûn
@nan
1999 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի մարտին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Luminal loop of the ryanodine receptor: a pore-forming segment?
@ast
Luminal loop of the ryanodine receptor: a pore-forming segment?
@en
Luminal loop of the ryanodine receptor: a pore-forming segment?
@nl
type
label
Luminal loop of the ryanodine receptor: a pore-forming segment?
@ast
Luminal loop of the ryanodine receptor: a pore-forming segment?
@en
Luminal loop of the ryanodine receptor: a pore-forming segment?
@nl
prefLabel
Luminal loop of the ryanodine receptor: a pore-forming segment?
@ast
Luminal loop of the ryanodine receptor: a pore-forming segment?
@en
Luminal loop of the ryanodine receptor: a pore-forming segment?
@nl
P2093
P2860
P356
P1476
Luminal loop of the ryanodine receptor: a pore-forming segment?
@en
P2093
P2860
P304
P356
10.1073/PNAS.96.7.3345
P407
P577
1999-03-01T00:00:00Z