Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen
about
7-Substituted pterins provide a new direction for ricin A chain inhibitorsOptimized 5-Membered Heterocycle-Linked Pterins for the Inhibition of Ricin Toxin ASmall-molecule inhibitor leads of ribosome-inactivating proteins developed using the doorstop approachIdentification of small molecules that suppress ricin-induced stress-activated signaling pathwaysBaicalin inhibits the lethality of ricin in mice by inducing protein oligomerization.Shiga toxin pathogenesis: kidney complications and renal failure.Identification of Small Molecule Inhibitors of Clostridium perfringens ε-Toxin Cytotoxicity Using a Cell-Based High-Throughput ScreenDevelopment of a quantitative RT-PCR assay to examine the kinetics of ribosome depurination by ribosome inactivating proteins using Saccharomyces cerevisiae as a model.Real-time cytotoxicity assay for rapid and sensitive detection of ricin from complex matricesSelective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.Novel class of potential therapeutics that target ricin retrograde translocation.Antisecretory factor peptide AF-16 inhibits the secreted autotransporter toxin-stimulated transcellular and paracellular passages of fluid in cultured human enterocyte-like cellsPassive and active vaccination strategies to prevent ricin poisoning.A relatively low level of ribosome depurination by mutant forms of ricin toxin A chain can trigger protein synthesis inhibition, cell signaling and apoptosis in mammalian cells.Immunotoxins: the role of the toxin.Structure-based design of ricin inhibitors.Inhibitors of the cellular trafficking of ricin.Targeting bacterial toxins.Toxicity of ricin A chain is reduced in mammalian cells by inhibiting its interaction with the ribosome.Treatments for Pulmonary Ricin Intoxication: Current Aspects and Future Prospects.A Cell-Based Fluorescent Assay to Detect the Activity of AB Toxins that Inhibit Protein Synthesis.Functional Assays for Measuring the Catalytic Activity of Ribosome Inactivating Proteins.
P2860
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P2860
Identification of small-molecule inhibitors of ricin and shiga toxin using a cell-based high-throughput screen
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Identification of small-molecu ...... l-based high-throughput screen
@ast
Identification of small-molecu ...... l-based high-throughput screen
@en
Identification of small-molecu ...... -based high-throughput screen.
@nl
type
label
Identification of small-molecu ...... l-based high-throughput screen
@ast
Identification of small-molecu ...... l-based high-throughput screen
@en
Identification of small-molecu ...... -based high-throughput screen.
@nl
prefLabel
Identification of small-molecu ...... l-based high-throughput screen
@ast
Identification of small-molecu ...... l-based high-throughput screen
@en
Identification of small-molecu ...... -based high-throughput screen.
@nl
P2093
P2860
P1433
P1476
Identification of small-molecu ...... l-based high-throughput screen
@en
P2093
Jon D Robertus
Paul G Wahome
P2860
P304
P356
10.1016/J.TOXICON.2010.03.016
P577
2010-03-27T00:00:00Z