Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages. - Wikidata - wikimedia - TriplyDB

Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.

Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.

http://www.wikidata.org/entity/Q33559576

about

Highly compacted biodegradable DNA nanoparticles capable of overcoming the mucus barrier for inhaled lung gene therapy Harnessing alveolar macrophages for sustained mucosal T-cell recall confers long-term protection to mice against lethal influenza challenge without clinical disease.A shift from cell cultures to creatures: in vivo imaging of small animals in experimental regenerative medicine.Intracellular bacillary burden reflects a burst size for Mycobacterium tuberculosis in vivo.Cytosolic, autocrine alpha-1 proteinase inhibitor (A1PI) inhibits caspase-1 and blocks IL-1β dependent cytokine release in monocytes.Assessment of F/HN-pseudotyped lentivirus as a clinically relevant vector for lung gene therapy Diminished Memory T-Cell Expansion Due to Delayed Kinetics of Antigen Expression by Lentivectors.Ozone inhalation promotes CX3CR1-dependent maturation of resident lung macrophages that limit oxidative stress and inflammation.Inhibition of p-IκBα Ubiquitylation by Autophagy-Related Gene 7 to Regulate Inflammatory Responses to Bacterial Infection Mitochondrial iron chelation ameliorates cigarette smoke-induced bronchitis and emphysema in mice.Airway gene transfer in a non-human primate: lentiviral gene expression in marmoset lungs.Multilineage transduction of resident lung cells in vivo by AAV2/8 for α1-antitrypsin gene therapy.Mycobacterium leprae Activates Toll-Like Receptor-4 Signaling and Expression on Macrophages Depending on Previous Bacillus Calmette-Guerin Vaccination Preparation for a first-in-man lentivirus trial in patients with cystic fibrosis.High efficiency gene transfer to airways of mice using influenza hemagglutinin pseudotyped lentiviral vectors.JNK suppresses pulmonary fibroblast elastogenesis during alveolar development.Current status and future directions of gene and cell therapy for cystic fibrosis.Elastase-induced pulmonary emphysema: insights from experimental models.Expert opinion in biological therapy: update on developments in lung gene transfer.Current status of gene therapy for α-1 antitrypsin deficiency.Lung surfactant metabolism: early in life, early in disease and target in cell therapy.Lentiviral delivery of RNAi for in vivo lineage-specific modulation of gene expression in mouse lung macrophages.Emergence of a stage-dependent human liver disease signature with directed differentiation of alpha-1 antitrypsin-deficient iPS cells.TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis.Brief report: VGLL4 is a novel regulator of survival in human embryonic stem cells.Construction of a lentiviral T/A vector for direct analysis of PCR-amplified promoters.Pulmonary research in 2013 and beyond: a National Heart, Lung, and Blood Institute perspective.Pluripotent stem cell differentiation reveals distinct developmental pathways regulating lung- versus thyroid-lineage specification.Zbtb7a induction in alveolar macrophages is implicated in anti-HLA-mediated lung allograft rejection.Alveolar-like Stem Cell-derived Myb(-) Macrophages Promote Recovery and Survival in Airway Disease.Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling.Practical Methods for Assessing Emphysema Severity Based on Estimation of Linear Mean Intercept (Lm) in the Context of Animal Models of Alpha-1 Antitrypsin Deficiency.[Study of the antitumor activity of alveolar macrophages after transfected human INF-γ gene].

P2860

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P2860

Amelioration of emphysema in mice through lentiviral transduction of long-lived pulmonary alveolar macrophages.

http://www.wikidata.org/entity/Q33559576

description

2009 nî lūn-bûn

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2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

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2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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Amelioration of emphysema in m ...... ulmonary alveolar macrophages.

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Amelioration of emphysema in m ...... ulmonary alveolar macrophages.

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Amelioration of emphysema in m ...... ulmonary alveolar macrophages.

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Journal of Clinical Investigation

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Amelioration of emphysema in m ...... ulmonary alveolar macrophages.

@en

P2093

Avi-Hai Hovav

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Bela Suki

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Hiroshi Hamakawa

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Letty W Kwok

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Richard C Mulligan

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Sreedevi Srinivasan

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P2860

Disruption of the murine alpha1-antitrypsin/PI2 gene

In vivo gene delivery and stable transduction of nondividing cells by a lentiviral vector

Early emphysema in the tight skin and pallid mice: roles of microfibril-associated glycoproteins, collagen, and mechanical forces.

Woodchuck hepatitis virus posttranscriptional regulatory element enhances expression of transgenes delivered by retroviral vectors.

The macrophage in chronic obstructive pulmonary disease.

Vesicular stomatitis virus G-pseudotyped lentivirus vectors mediate efficient apical transduction of polarized quiescent primary alveolar epithelial cells.

Development of retroviral vectors for gene transfer to airway epithelia.

Elastin fragments drive disease progression in a murine model of emphysema

Lentivirus vectors pseudotyped with filoviral envelope glycoproteins transduce airway epithelia from the apical surface independently of folate receptor alpha

Gene therapy progress and prospects: alpha-1 antitrypsin.

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10.1172/JCI36666

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1

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120

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Darrell N Kotton

George J Murphy

Andrew A Wilson

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2009-12-21T00:00:00Z

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20038801

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2798672

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