Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins
about
Functional redundancy between the XLF and DNA-PKcs DNA repair factors in V(D)J recombination and nonhomologous DNA end joiningKu70-deficient embryonic stem cells have increased ionizing radiosensitivity, defective DNA end-binding activity, and inability to support V(D)J recombinationDefective DNA repair and increased genomic instability in Artemis-deficient murine cellsT-cell receptor gene rearrangements in functional T-cell clones from severe combined immune deficient (scid) mice: reversion of the scid phenotype in individual lymphocyte progenitors.Preferential rearrangement of V kappa 4 gene segments in pre-B cell lines.Light-chain gene expression before heavy-chain gene rearrangement in pre-B cells transformed by Epstein-Barr virusIrradiation promotes V(D)J joining and RAG-dependent neoplastic transformation in SCID T-cell precursors.Gene targeting in the Ig kappa locus: efficient generation of lambda chain-expressing B cells, independent of gene rearrangements in Ig kappaMechanisms of double-strand break repair in somatic mammalian cells.Ataxia telangiectasia-mutated protein and DNA-dependent protein kinase have complementary V(D)J recombination functions.A novel germ-line JK transcript starting immediately upstream of JK1An essential role for CtIP in chromosomal translocation formation through an alternative end-joining pathwayCharacterization of hu-PBL-SCID mice with high human immunoglobulin serum levels and graft-versus-host disease.Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell developmentNonsense mutation at Tyr-4046 in the DNA-dependent protein kinase catalytic subunit of severe combined immune deficiency miceT cell receptor gamma and delta gene junctional sequences in SCID mice: excessive P nucleotide insertionSevere combined immunodeficiency (SCID) in man: B cell-negative (B-) SCID patients exhibit an irregular recombination pattern at the JH locus.N region diversity of a transgenic substrate in fetal and adult lymphoid cellsThe chromosome translocation (11;14)(p13;q11) associated with T cell acute leukemia. Asymmetric diversification of the translocational junctions.Normal recombination substrate VH to DJH rearrangements in pre-B cell lines from scid miceRestricted kappa chain expression in early ontogeny: biased utilization of V kappa exons and preferential V kappa-J kappa recombinationsHigh frequency of normal DJH joints in B cell progenitors in severe combined immunodeficiency mice.Extended duration of DH-JH rearrangement in immunoglobulin heavy chain transgenic mice: implications for regulation of allelic exclusion.Ku70 is required for late B cell development and immunoglobulin heavy chain class switching.Unexpected rearrangement and expression of the immunoglobulin lambda1 locus in scid mice.Biochemical and genetic defects in the DNA-dependent protein kinase in murine scid lymphocytes.Biased T-cell receptor delta element recombination in scid thymocytes.Strand breaks without DNA rearrangement in V (D)J recombination.Wild-type V(D)J recombination in scid pre-B cellsIdentification of a nonsense mutation in the carboxyl-terminal region of DNA-dependent protein kinase catalytic subunit in the scid mouseA link between double-strand break-related repair and V(D)J recombination: the scid mutation.Development of B-lineage cells in the bone marrow of scid/scid mice following the introduction of functionally rearranged immunoglobulin transgenes.DNA-PK is essential only for coding joint formation in V(D)J recombinationAlternative pathways for the repair of RAG-induced DNA breaksMolecular requirements for the mu-induced light chain gene rearrangement in pre-B cells.Murine lambda gene rearrangements: the stochastic model prevails over the ordered model.Stimulation of kappa light-chain gene rearrangement by the immunoglobulin mu heavy chain in a pre-B-cell lineUnequal signal and coding joint formation in human V(D)J recombination.RAG-1 and RAG-2 are not sufficient to direct all phases of immunoglobulin gene rearrangement in pre-B-cell lines.Different capacities for recombination in closely related human lymphoblastoid cell lines with different mutational responses to X-irradiation.
P2860
Q24624166-F87896E9-7577-4DA3-A21E-A37BF9193B02Q28243620-D53F51BC-C550-4162-9C31-C30A024C894AQ28513655-C35CC6F1-BE89-49FC-8E12-2BDC6B8A220DQ33565037-333DF727-F4E4-4220-80EA-E8FEE1A26709Q33771048-8BA3FD51-FC92-4995-9E79-32068EFADBF7Q33847682-2916719A-11B3-497B-92E9-5BB94DD54046Q33966818-BEF75BBE-0092-45BF-A00D-5810F38E4147Q34044604-30B15F78-2C13-43A8-89E9-F7E721F89D29Q34317108-B663FC0F-DB7B-4EBC-9E5F-94804E1B7874Q34549990-D4B4F491-A135-4788-BEA0-ACF58F15C955Q35248780-F4CFBA00-D487-4C02-9306-B5D506875203Q35682245-9C8E57B1-7092-409D-AA82-03FA6D15F376Q35832063-859AA588-D8A3-43F2-A758-144AD9C32A3CQ36041356-CC59CBA8-EF34-4F47-91EE-D810407CD472Q36044979-5EBAF52A-873E-4016-A36A-D45168E51D6CQ36230427-C6466D9A-CC9D-41CB-BB05-6129B3044283Q36230546-F7D5FDE9-6147-4901-90F4-69CEF4B1CA26Q36232012-4A79BBEA-89D2-421A-BB0D-69B49EFAED1CQ36350507-F64442A1-DCAD-41C3-AB47-9C7261950C0EQ36351283-CE44FB08-2262-4506-9892-168717E59953Q36361665-2EC1F43C-EF66-4B9B-BC2F-10DC8D8E43ABQ36362310-93E83FB4-AAAD-4578-BC13-2A995FD2D2E4Q36368087-E9BACE4E-1B00-4FE3-949A-E60958503A77Q36401127-08397891-883B-4840-B0A3-EF86EE641B8BQ36404655-D8DC818F-10C4-4F18-A311-05B467668ACFQ36562716-A77892EC-686C-45A1-A99E-573E9FD469BDQ36686717-0BABF1B4-2104-4978-9584-0AB253848F96Q36696533-79640630-5954-4B2D-B90B-B475EC14AE85Q36728878-D37E1214-1CDD-4B51-B660-3CB7D7676456Q36820879-2A87881B-DAD9-4F15-8B7D-D602788C09E3Q37508055-4EEE49D6-632B-46D1-8273-11954FCFE563Q37733497-A819E9E6-77DD-4215-BEC7-E9842672F6E5Q39724861-5F3B016C-F580-44DB-926B-DB8DD778A996Q40724946-37EE8B4F-4AA7-4D94-807F-3877DB9356E7Q41081737-377648FC-6AF1-4C10-806D-CE2AE5A77884Q41202410-9E874218-9FCC-438A-A79E-460B69635128Q41530237-264DEE08-989B-42CE-B4A3-AEA54A49AB68Q41545122-26025F96-499E-4019-95C4-925EC867455EQ41545128-D08D4DB9-ECC9-4647-8175-E97F9330F0DAQ42167788-E7526BDD-DD87-4980-BC02-37933694777A
P2860
Isolation of scid pre-B cells that rearrange kappa light chain genes: formation of normal signal and abnormal coding joins
description
1989 nî lūn-bûn
@nan
1989 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի մարտին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@ast
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@en
Isolation of scid pre-B cells ...... nal and abnormal coding joins.
@nl
type
label
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@ast
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@en
Isolation of scid pre-B cells ...... nal and abnormal coding joins.
@nl
prefLabel
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@ast
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@en
Isolation of scid pre-B cells ...... nal and abnormal coding joins.
@nl
P2093
P2860
P1433
P1476
Isolation of scid pre-B cells ...... gnal and abnormal coding joins
@en
P2093
B A Malynn
G D Yancopoulos
R A Phillips
R R Pollock
T K Blackwell
P2860
P304
P407
P577
1989-03-01T00:00:00Z