IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression
about
The Myc target gene JPO1/CDCA7 is frequently overexpressed in human tumors and has limited transforming activity in vivoLymphoid hyperplasia and lymphoma in transgenic mice expressing the small non-coding RNA, EBER1 of Epstein-Barr virusTriplication of a 21q22 region contributes to B cell transformation through HMGN1 overexpression and loss of histone H3 Lys27 trimethylation.Dual role of RAG2 in V(D)J recombination: catalysis and regulation of ordered Ig gene assembly.High-frequency disruption of the N-myc gene in embryonic stem and pre-B cell lines by homologous recombination.N-myc can functionally replace c-myc in murine development, cellular growth, and differentiationHigh-level DNA amplifications are common genetic aberrations in B-cell neoplasms.High frequency of myelomonocytic tumors in aging E mu L-myc transgenic mice.Artemis and p53 cooperate to suppress oncogenic N-myc amplification in progenitor B cells.Differential regulation of the N-myc gene in transfected cells and transgenic mice.A novel fluorescence-based system for assaying and separating live cells according to VDJ recombinase activityChromosomal location targets different MYC family gene members for oncogenic translocationsS region transcription per se promotes basal IgE class switch recombination but additional factors regulate the efficiency of the process.MYCN is a novel oncogenic target in pediatric T-cell acute lymphoblastic leukemia.Identification of cooperative genes for E2A-PBX1 to develop acute lymphoblastic leukemia.Single exchanges of amino acids in the basic region change the specificity of N-Myc.Cyclin D1/bcl-1 cooperates with myc genes in the generation of B-cell lymphoma in transgenic mice.Negative autoregulation of c-myc transcription.IgH enhancer deregulated expression of L-myc: abnormal T lymphocyte development and T cell lymphomagenesis.Surface IgM mediated regulation of RAG gene expression in E mu-N-myc B cell linesDomains of human c-myc protein required for autosuppression and cooperation with ras oncogenes are overlapping.Identification of BSAP (Pax-5) target genes in early B-cell development by loss- and gain-of-function experiments.Mechanism of endogenous myc gene down-regulation in E mu-N-myc tumors.
P2860
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P2860
IgH enhancer-mediated deregulation of N-myc gene expression in transgenic mice: generation of lymphoid neoplasias that lack c-myc expression
description
1989 nî lūn-bûn
@nan
1989 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1989 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
name
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@ast
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@en
IgH enhancer-mediated deregula ...... as that lack c-myc expression.
@nl
type
label
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@ast
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@en
IgH enhancer-mediated deregula ...... as that lack c-myc expression.
@nl
prefLabel
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@ast
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@en
IgH enhancer-mediated deregula ...... as that lack c-myc expression.
@nl
P2093
P2860
P1433
P1476
IgH enhancer-mediated deregula ...... ias that lack c-myc expression
@en
P2093
K Zimmerman
P2860
P304
P407
P577
1989-04-01T00:00:00Z